Could 'Good Bacteria' capsules beat BV without antibiotics?

NCT ID NCT07418996

First seen Feb 20, 2026 · Last updated Jun 24, 2026 · Updated 15 times

Summary

This study tested whether vaginal capsules containing live lactobacilli (good bacteria) are safe and tolerable for treating bacterial vaginosis (BV), a common vaginal infection. Fifty-seven women with BV received either the lactobacillus capsules or the standard antibiotic metronidazole. The main goal was to check for side effects, with secondary goals looking at cure and recurrence rates.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Guangdong Longchuangji Pharmaceutical Co., Ltd.

    Chaozhou, Guangdong, 521000, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

live lactobacillus vaginal capsules

What this could lead to

If successful, this could offer a new, gentler treatment option for bacterial vaginosis that uses good bacteria instead of antibiotics.

What could go wrong

This is an early Phase 2a trial with only 57 participants, so results may not apply to everyone. The treatment may not work better than existing options or could cause side effects.

Conditions

The condition(s) this trial relates to.

bacterial vaginosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.