Endometriosis sex pain: is your brain making it worse?

NCT ID NCT03216330

First seen Apr 18, 2026 · Last updated Jun 23, 2026 · Updated 9 times

Summary

This study looked at 56 women with endometriosis to see if severe pain during sex is linked to a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Researchers used pain-pressure tests and daily surveys over 6 weeks to measure pain levels. The goal was to better understand the connection, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • BC Children's and Women's Hospital

    Vancouver, British Columbia, V6H2N9, Canada

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better understand why some women with endometriosis have severe pain during sex, potentially guiding future treatments.

What could go wrong

This is a small observational study with no treatment being tested, so it won't directly lead to new therapies. Results may not apply to all women with endometriosis.

Conditions

The condition(s) this trial relates to.

endometriosis psychologic dyspareunia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.