New study tests drug to ease pain during fertility treatment for endometriosis patients
NCT ID NCT04002141
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested whether the drug letrozole can reduce pain during ovarian stimulation in 60 women with endometriosis. Participants received either letrozole or a placebo daily, and researchers measured changes in pain scores. The goal is to find a way to make fertility treatments less painful for those with endometriosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Letrozole
What this could lead to
If it works, this could offer a way to manage pain during fertility treatments for women with endometriosis.
What could go wrong
This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Letrozole may not reduce pain or could have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UCSF Center for Reproductive Health
San Francisco, California, 94158, United States