Ovarian hyperstimulation syndrome
MONDO:0011972A complication of ovulation induction in infertility treatment. It is graded by the severity of symptoms which include ovary enlargement, multiple ovarian follicles; ovarian cysts; ascites; and generalized edema. The full-blown syndrome may lead to renal failure, respiratory distress, and even death. Increased capillary permeability is caused by the vasoactive substances, such as vascular endothelial growth factors, secreted by the overly-stimulated ovaries.
Also known as: OHSS, ovarian hyperstimulation syndrome, ovarian hyperstimulation syndrome, familial gestational spontaneous
11 clinical trials for this condition and its sub-types.
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New hope for IVF patients: drug may prevent dangerous ovarian overreaction
Disease control Recruiting nowThis study compares two methods to prevent ovarian hyperstimulation syndrome (OHSS), a serious side effect of fertility treatments. About 150 women at high risk for OHSS will receive either cabergoline or a standard 'coasting' procedure. The goal is to see which approach better r…
Phase: PHASE2 • Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Which IVF stimulation is easier on patients? new study aims to find out
Symptom relief Recruiting nowThis study compares two different ovarian stimulation methods used in IVF to see which one patients prefer and tolerate better. Sixty women undergoing either fertility preservation or preimplantation genetic testing will try both methods in a crossover design. The main goal is to…
Phase: PHASE4 • Sponsor: University Hospital, Ghent • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Measuring follicle volume could improve IVF timing for poor responders
Knowledge-focused Recruiting nowThis study looks at 100 women with very low ovarian reserve (fewer than 4 follicles) undergoing IVF. Researchers will measure the volume of each follicle just before the trigger shot that matures the eggs. They want to see if follicle volume is a better predictor of egg maturity …
Sponsor: ART Fertility Clinics LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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FSH blood tests during IVF could personalize doses
Knowledge-focused Recruiting nowThis study looks at whether tracking FSH levels during ovarian stimulation can help predict how many eggs a woman will produce. Researchers will monitor 150 women undergoing IVF to find the ideal FSH range for better outcomes. The goal is to tailor hormone doses to each patient, …
Sponsor: ART Fertility Clinics LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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AI vs. doctors: who picks the best day for IVF?
Knowledge-focused Recruiting nowThis study tests whether an artificial intelligence program called STIMAI® can help choose the best day to give the final 'trigger' shot in IVF, compared to doctors making the decision alone. About 644 women undergoing ovarian stimulation for IVF will be randomly assigned to eith…
Phase: NA • Sponsor: Fundacion Dexeus • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC