Faster recovery after cervical stitch: Shorter-Acting spinal anesthetic tested

NCT ID NCT04394533

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether a shorter-acting spinal anesthetic (prilocaine) helps pregnant women recover feeling and movement faster after a cervical stitch procedure compared to the standard drug (bupivacaine). About 129 healthy pregnant women at risk of preterm loss will receive one of the two drugs via spinal injection. The goal is to see if prilocaine allows quicker return of leg strength and sensation, enabling earlier hospital discharge and less need for a urinary catheter.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Prilocaine (hyperbaric 2%) and Bupivacaine (hyperbaric 0.5%)

What this could lead to

If prilocaine works better, women could recover feeling and movement faster after a cervical stitch, leaving the hospital sooner and avoiding a urinary catheter.

What could go wrong

This is a small, single-center trial. The benefit may be modest, and prilocaine might not provide enough numbness for the procedure in some cases.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical incompetence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE1 7RT, United Kingdom