Faster recovery after cervical stitch: Shorter-Acting spinal anesthetic tested
NCT ID NCT04394533
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether a shorter-acting spinal anesthetic (prilocaine) helps pregnant women recover feeling and movement faster after a cervical stitch procedure compared to the standard drug (bupivacaine). About 129 healthy pregnant women at risk of preterm loss will receive one of the two drugs via spinal injection. The goal is to see if prilocaine allows quicker return of leg strength and sensation, enabling earlier hospital discharge and less need for a urinary catheter.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Prilocaine (hyperbaric 2%) and Bupivacaine (hyperbaric 0.5%)
- What this could lead to
- If prilocaine works better, women could recover feeling and movement faster after a cervical stitch, leaving the hospital sooner and avoiding a urinary catheter.
- What could go wrong
- This is a small, single-center trial. The benefit may be modest, and prilocaine might not provide enough numbness for the procedure in some cases.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Guy's and St Thomas' NHS Foundation Trust
London, SE1 7RT, United Kingdom