Could a laser ease painful sex for millions of women?

NCT ID NCT05597358

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether high-intensity laser therapy (HILT) can reduce pain during intercourse for women with provoked vestibulodynia, a condition causing severe pain at the vaginal opening. About 145 women with moderate to severe pain will receive either real or sham laser treatments twice a week for six weeks. Researchers will measure changes in pain, sexual function, and quality of life up to six months after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
High Intensity Laser Therapy (Nd:Yag 1064 nm)
What this could lead to
If effective, this could offer a non-drug, non-surgical option to reduce pain during intercourse for women with provoked vestibulodynia.
What could go wrong
This is a relatively small trial (145 participants) testing a device, and the sham group may also show improvement due to placebo effects. Long-term benefits are not yet known.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire de Québec - Université Laval

    Québec, Quebec, G1V 4G2, Canada

  • Centre hospitalier universitaire de Sherbrooke

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Exogenia

    Sherbrooke, Quebec, J1L 1C6, Canada

  • Kinatex l'Ormière

    Québec, Quebec, G2B 3K3, Canada

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