Memorial Sloan Kettering Cancer Center

This study is testing whether adding the immunotherapy drug nivolumab to standard ABVD chemotherapy can improve cure rates for people with high-risk Hodgkin lymphoma. The trial focuses on patients whose cancer shows signs of being resistant after initial chemotherapy. Researchers…

This study is testing whether a pill called erdafitinib can shrink recurrent bladder tumors in people with a specific genetic change (FGFR3 mutation). The drug is taken for a short period before a standard procedure to remove the tumor. Researchers want to see if this targeted ap…

This early-stage trial is testing the safety of a new treatment called CAR T-cell therapy for people with advanced multiple myeloma, a type of blood cancer. Doctors modify a patient's own immune cells to better target and fight the cancer cells. The study also explores whether ad…

This study is testing whether the drug amivantamab is a safe and effective treatment for people with advanced stomach or esophageal cancer that has specific genetic changes (EGFR or MET amplification). The trial will enroll about 25 adults whose cancer has worsened after at least…

This study is testing an experimental drug called CPI-613 in people with aggressive types of lymphoma or leukemia that have come back or stopped responding to standard treatments. The main goal is to see if the drug is safe and can help shrink the cancer. The trial is for adults …

This study is testing whether immunotherapy drugs given before bladder cancer surgery are safe and can shrink tumors to make surgery more successful. The trial includes 52 patients with muscle-invasive bladder cancer who cannot receive standard chemotherapy. Researchers are compa…

This small, early-stage study is testing whether a drug called romosozumab can help strengthen bones and slow bone damage in postmenopausal women who have both multiple myeloma and osteoporosis. Researchers will measure changes in bone health markers and closely monitor safety. T…

This study is testing whether some patients with a common type of early-stage breast cancer can safely avoid a more extensive lymph node removal surgery. Researchers want to see if using a less invasive procedure is sufficient for patients whose cancer has spread to 1 or 2 lymph …

This study is testing a drug called neratinib in children and young adults whose solid tumors, brain tumors, lymphoma, or leukemia have returned or did not respond to standard treatments. The main goals are to find a safe dose and see what effects, both good and bad, the drug has…

This study is testing whether a combination of three drugs—temozolomide, cisplatin, and nivolumab—can help control advanced colorectal cancer that has stopped responding to standard chemotherapy. It is for patients whose tumors have a specific genetic profile (MMR-proficient). Th…

This early-stage trial is testing the safety of a single, high-precision radiation treatment for cancer that has spread to the spine and grown back after previous radiation. It aims to control tumor growth in the spine while carefully monitoring for side effects. The study will e…

This study is testing a specific combination of chemotherapy drugs (irinotecan and carboplatin) as the first treatment for children and young adults newly diagnosed with intermediate- or high-risk rhabdomyosarcoma, a type of muscle cancer. The goal is to see how well the tumor re…

This study is testing a new treatment order for people with cancer that has spread to their bones and needs surgery to prevent a break. Researchers want to see if giving a very precise, high-dose radiation treatment (SBRT) less than a week before the bone-stabilizing surgery is s…

This study is testing whether combining two existing drugs, pembrolizumab and gemcitabine, can help control advanced forms of a rare skin cancer called mycosis fungoides or Sézary syndrome. It is for adults whose disease has worsened after at least one prior treatment. The main g…

This study is testing whether a detailed health assessment can help doctors personalize the intensity of a stem cell transplant for older adults (age 60+) with certain blood cancers. The assessment looks at factors like thinking skills, physical ability, and mood to decide if a p…

This early-stage study is testing whether combining three drugs—belantamab mafodotin, nirogacestat, and pomalidomide—is safe for people with multiple myeloma that has returned or stopped responding to previous treatments. Researchers are enrolling just 9 participants who have alr…

This study is testing whether a chemotherapy combination commonly used to treat children with acute lymphoblastic leukemia (ALL) is safe and effective for adults aged 18-60 with newly diagnosed ALL. The goal is to see if this 'pediatric-inspired' approach can help adults achieve …

This study is testing whether a drug called ado-trastuzumab emtansine can help control advanced solid tumors that have specific abnormalities in the HER2 gene. The trial is enrolling adults with cancers like lung, bladder, and urinary tract cancers that have these genetic feature…

This study is testing whether combining two drugs, pembrolizumab and olaparib, can better control advanced pancreatic cancer that has spread. The treatment is for patients whose cancer has stopped growing or shrunk while on platinum-based chemotherapy. Researchers want to see if …

This study is testing whether adding a drug called glucarpidase (Voraxaze) to the standard treatment for central nervous system lymphoma helps the body clear the chemotherapy drug methotrexate more quickly. The goal is to see if this faster clearance reduces potential side effect…

This study investigates whether giving a higher dose of a patient's own stem cells during transplant leads to better immune system recovery and outcomes for people with aggressive lymphoma that has returned or resisted treatment. Participants with relapsed or refractory diffuse l…

This study is testing whether adding an over-the-counter antioxidant called N-Acetylcysteine (NAC) to a powerful cell therapy (CAR-T) is safe for people with lymphoma. Researchers want to find the highest dose of NAC that causes few or mild side effects when given alongside the C…

This study is testing whether people with multiple myeloma who are in a deep, sustained remission can safely stop their maintenance therapy. Researchers want to see if active monitoring without ongoing treatment can keep the cancer in remission for at least one year. The goal is …

This early-stage study is testing a personalized cell therapy called lifileucel for patients whose melanoma has spread to the brain and is no longer responding to standard immunotherapy. Doctors will collect a patient's own tumor-fighting immune cells, grow them in a lab, and inf…

This study compares two approaches to help cancer patients quit smoking before their surgery. Researchers are testing whether gradually reducing smoking before quitting works better than standard counseling and nicotine patches alone. The goal is to find the most effective way to…

This study is testing whether giving an extra-high dose of radiation directly to the main prostate tumor, while treating the rest of the prostate with a standard dose, can better control intermediate-risk prostate cancer. Researchers want to see if this 'boost' approach can cut t…

This small, early-stage study is testing whether the immunotherapy drug pembrolizumab can help control the growth of recurrent malignant brain tumors (gliomas) in a specific group of patients. The drug works by activating the body's own immune system to attack cancer cells. Resea…

This study is testing whether adding an experimental drug called RP-3500 to standard radiation therapy is safe and can help control cancer that has spread. It is for people with advanced solid tumors who have a specific change in their ATM gene. The main goals are to find the saf…

This study aims to find the most effective way to help smokers quit or cut down when they come in for lung cancer screening. Researchers are testing different treatment approaches at established screening centers to create a practical blueprint that doesn't overburden staff. The …

This early-stage study is checking if it's safe and practical to give a drug called nivolumab (an immunotherapy) along with standard chemotherapy before surgery for a type of lung cancer called malignant pleural mesothelioma. The main goal is to see if this combination treatment …

This study is testing how well and how safely the diabetes drug glipizide works to lower high blood sugar in people with pancreatic cancer. It involves 29 participants who have active pancreatic cancer and high blood sugar levels. Researchers are comparing blood sugar levels befo…

This study is testing which type of food assistance works best to help cancer patients complete their treatment. Researchers are comparing three options: monthly food vouchers, weekly grocery deliveries, and a hospital food pantry. They want to see if making sure patients have en…

This study is testing whether a combination of two drugs, pembrolizumab and lenvatinib, can help control advanced uterine or ovarian carcinosarcoma, a rare and aggressive cancer. It is for up to 40 patients whose cancer has continued to grow after at least one prior chemotherapy …

This study tested whether giving smokers information about how smoking harms their oral health during a routine dental visit would help them quit. It involved over 1,000 patients who smoked at least 10 cigarettes a day and were visiting an NYU dental clinic. Researchers compared …

This study tests whether adding the immunotherapy drug pembrolizumab to standard BCG treatment helps control high-risk bladder cancer in patients who want to avoid having their bladder removed. The trial involves 45 participants with early-stage but aggressive cancer that has a h…

This study is testing whether combining an immunotherapy drug called PDR001 with other targeted cancer drugs is safe and effective for treating advanced thyroid cancer that no longer responds to standard radioactive iodine treatment. The trial includes 19 adults with specific typ…

This study is testing whether combining two existing cancer drugs, nivolumab and cabozantinib, is safe and effective for people with advanced non-clear cell kidney cancer that has spread. The trial will enroll about 60 adults who have had limited prior treatment to see if the com…

This study is testing whether combining two drugs—an oral targeted therapy (vemurafenib) and an immunotherapy infusion (obinutuzumab)—can effectively treat adults with hairy cell leukemia who haven't had any prior treatment. The goal is to achieve a complete remission, meaning no…

This study is testing whether the immunotherapy drug pembrolizumab can shrink early-stage NK/T-cell lymphoma in patients who haven't received chemotherapy yet. The trial involves 19 participants with this rare cancer affecting the nasal and throat areas. Researchers want to see h…

This study is testing whether adding an immunotherapy drug called durvalumab to a precise form of radiation therapy (SBRT) works better than radiation alone for early-stage lung cancer. It is for patients with a higher risk of their cancer returning who are not candidates for sur…

This study is testing whether adding two experimental vaccines (IO102/IO103) to standard immunotherapy drugs (nivolumab and relatlimab) is safe and effective for people with advanced melanoma that can't be surgically removed. The trial involves 43 adults who haven't received any …

This study is testing whether people with chronic lymphocytic leukemia or small lymphocytic lymphoma can safely stop their venetoclax treatment when blood tests show no detectable cancer cells. Researchers will follow 81 patients who stop treatment to see if they remain cancer-fr…

This study aims to find out which of two maintenance drugs helps people with multiple myeloma feel better and live better after their initial treatment is successful. It compares the standard drug, lenalidomide, against a newer drug, daratumumab, focusing on patients' reported qu…

This study is testing whether adding two chemotherapy drugs, irinotecan and temozolomide, to the standard treatment can better control Ewing sarcoma, a type of bone and soft tissue cancer. It involves 83 patients aged 1 to 40 who are newly diagnosed and have not yet received trea…

This study is testing whether giving two immunotherapy drugs (nivolumab and ipilimumab) before surgery can shrink melanoma tumors and prevent the cancer from coming back. It involves 28 adults with stage III melanoma that can be surgically removed. The research also explores a ne…

This study is testing whether regular treadmill walking at home affects markers that indicate how aggressive prostate cancer might become. It involves 36 men with low-risk prostate cancer who are being monitored rather than immediately treated. Participants are assigned to either…

This study is testing how well a combination of two drugs, venetoclax and obinutuzumab, works for people with chronic lymphocytic leukemia (CLL) who have not yet received any treatment. It aims to see if this combination can control the cancer and delay its progression. The trial…

This study is testing whether a simple smartphone app that sends text message reminders can help people with breast cancer remember to take their medication, palbociclib (Ibrance), on the correct schedule. It involves 45 adults who are starting this medication for the first time.…

This early-stage study is testing whether HB-200 treatment can help people with HPV16-positive head and neck cancer who have completed standard treatment but still show signs of cancer DNA in their blood. The trial involves 7 patients who have no visible cancer on scans but test …

This study is testing whether adding a newer immunotherapy drug (atezolizumab) to standard chemotherapy (gemcitabine and cisplatin) is safe and effective for bladder cancer. It involves two groups of patients: those with cancer that has spread (metastatic) and those with cancer t…

This study is testing whether combining two immunotherapy drugs, NKTR-214 and nivolumab, can help control advanced sarcoma. It is for patients aged 12 and older whose cancer has progressed after at least one prior treatment. The main goal is to see how many patients' tumors shrin…

This early-stage study is testing the safety of a new personalized treatment for men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to better r…

This study is testing whether adding a new drug called MEK162 to the standard treatment (imatinib) works better for people with advanced gastrointestinal stromal tumors (GIST). The research first finds the safest dose, then checks if the combination helps shrink tumors and delays…

This study is testing whether adding an experimental drug (BMS-986205) to an existing immunotherapy (nivolumab) works better for controlling recurrent endometrial cancer. It is for women whose cancer has come back after initial platinum-based chemotherapy. The main goal is to see…

This study aims to find the best way to give high-dose radiation to control cancer that has spread to bones, the spine, soft tissue, or lymph nodes. It compares giving all the radiation in one day versus spreading it over three days, using precise imaging to target the tumor and …

This study is testing whether combining two existing cancer drugs, lenvatinib and pembrolizumab, is safe and effective for people with advanced sarcoma that cannot be removed by surgery. The trial will enroll 52 adults with specific types of advanced sarcoma who have tried 1-3 pr…

This study is testing whether a much lower dose of radiation, combined with standard chemotherapy, works as well as the current high-dose standard for treating HPV-positive throat cancer. It aims to control the cancer while potentially reducing long-term side effects from radiati…

This study is testing whether two existing cancer drugs, lenvatinib and pembrolizumab, work together to treat advanced salivary gland cancers that have come back or spread. It will involve about 64 adults whose cancer has progressed and is no longer curable with standard treatmen…

This study is testing whether waiting different lengths of time between completing chemo-radiation treatment and having surgery improves outcomes for people with stage II or III rectal cancer. Researchers are looking to see if a longer wait helps eliminate more cancer cells befor…

This study is testing whether the drug ensartinib can help control advanced melanoma that has specific genetic changes in the ALK gene. The trial is for patients whose cancer has continued to grow despite standard treatments like immunotherapy. Researchers want to see if this tar…

This early-stage study is testing whether adding three new drugs (irinotecan, temozolomide, and bevacizumab) to the standard high-dose chemotherapy can help control a rare and aggressive cancer called Desmoplastic Small Round Cell Tumor (DSRCT). The main goal is to see if this co…

This study is testing whether a new, shorter course of highly targeted radiation is a safe and practical way to treat intermediate-risk prostate cancer. It will involve 35 men and uses advanced MRI scans to aim the radiation very precisely at the main tumor and the entire prostat…

This study is testing whether combining two drugs, palbociclib and INCMGA00012, is a safe and effective treatment for people with advanced liposarcoma, a type of cancer that arises in fat tissue. The trial will enroll 42 adults to see if this combination can shrink or control the…

This early-stage study is testing whether combining a targeted radiation technique called IMPRINT with the immunotherapy drug pembrolizumab is safe for people with advanced malignant pleural mesothelioma. Researchers will first find the highest radiation dose that causes few or m…

This early-stage trial is testing the safety of a two-part treatment for aggressive B-cell non-Hodgkin lymphoma that has returned or not responded to other therapies. First, patients receive high-dose chemotherapy and a transplant of their own blood stem cells. Then, they receive…

This early-stage study is testing a new combination of chemotherapy drugs (RBM) given before a patient's own stem cells are transplanted back into them. The goal is to see if this regimen is safer and has fewer severe side effects than the standard treatment for older adults (age…

This early-phase study is testing whether combining two cancer drugs (cabozantinib and nivolumab) with targeted radiation is safe for people whose kidney cancer has spread to the brain. The main goal is to see if patients can tolerate this three-part treatment without severe side…

This early-stage study is testing whether combining two drugs, glofitamab and lenalidomide, is a safe and feasible treatment for adults with mantle cell lymphoma that has come back or stopped responding to other therapies. It is specifically for people whose cancer progressed aft…

This study is testing whether a maintenance therapy with the drug Ixazomib can help control AL amyloidosis and prevent it from coming back after patients have already responded to their first treatment. It involves 17 adults who have achieved at least a partial response to their …

This study is testing whether adding an immunotherapy drug called durvalumab to a precise, high-dose form of radiation is safe and effective for people with locally advanced pancreatic cancer. The goal is to better control the disease and see if the combination makes the tumor mo…

This early-stage trial is testing the safety of a new, personalized treatment approach for pancreatic cancer. After surgery to remove the tumor, patients receive an immunotherapy drug followed by a vaccine designed specifically for their cancer, and then standard chemotherapy. Th…

This study is testing whether adding the drug plinabulin to the standard drug pegfilgrastim helps white blood cell counts return to normal faster after a stem cell transplant for multiple myeloma. The goal is to reduce the dangerous period of low white blood cells (neutropenia) w…

This study is testing a shorter, more targeted form of radiation therapy for women with very early-stage breast cancer. Instead of radiating the entire breast for 5-7 weeks, doctors are giving radiation only to the area where the tumor was removed, over just 2 weeks. The main goa…

This study is testing whether combining two immunotherapy drugs can help control advanced sarcoma, a rare and aggressive cancer. The trial is for adults with certain types of sarcoma that have spread or cannot be surgically removed, and who have typically tried at least one other…

This study is testing a new, personalized way to calculate the dose of melphalan chemotherapy given to lymphoma patients before a stem cell transplant. Instead of using a standard dose based on height and weight, researchers are using a mathematical model to calculate an optimal …

This early-stage study is testing whether combining an experimental drug called TTI-622 with an existing myeloma treatment (daratumumab) is safe for people whose cancer has returned or stopped responding to other therapies. Researchers will first find the highest safe dose of the…

This study is testing whether combining a drug called durvalumab (an immunotherapy) with radiation therapy can help control locally advanced non-small cell lung cancer. It is for patients who are not eligible for the standard treatment of chemotherapy followed by radiation, often…

This study compares two radiation treatments for head and neck cancer to see which causes fewer side effects. Researchers are testing whether proton beam radiation causes less damage to healthy tissue than traditional photon radiation. The main goal is to see if patients receivin…

This study is testing whether giving two drugs, pembrolizumab and olaparib, before surgery can shrink certain types of breast cancer in people with specific genetic mutations. The goal is to see if this combination can reduce the tumor enough to improve surgical outcomes. The tri…

This study is testing whether N-acetylcysteine, a medication already used for other conditions, can help the immune system fight severe COVID-19. Researchers are giving it to 48 hospitalized patients who are either in intensive care on a ventilator or need significant oxygen supp…

This study compares two approaches to breast reconstruction after mastectomy for breast cancer. Researchers want to see if using a special surgical mesh called Acellular Dermal Matrix (ADM) leads to fewer complications than reconstruction without it. The trial involves 353 women …

This study aims to see if a test on a tumor sample taken before treatment can predict how well patients with advanced triple negative breast cancer will respond to a combination of cisplatin chemotherapy and radiation therapy. It involves about 49 patients whose cancer has return…

This study is testing whether a lab-made antibody called Hu3F8, given with an immune-boosting drug (GM-CSF), is safe and effective for treating high-risk neuroblastoma that has come back or resisted standard treatments. It involves about 186 patients, including children over 1 ye…

This study is testing whether combining two drugs, rucaparib and nivolumab, can help control advanced leiomyosarcoma (LMS), a rare type of cancer. It is for adults whose cancer has spread or cannot be removed by surgery and who have tried 1 to 3 other treatments. The main goal is…

This study is testing whether specific diets or a diabetes medication can prevent dangerous high blood sugar in people receiving a standard two-drug treatment for advanced breast cancer. Researchers want to see if controlling blood sugar helps the cancer therapy work better. The …

This study is testing whether two drugs, palifermin and leuprolide acetate, can help a patient's immune system recover more quickly after receiving a stem cell transplant from a donor. The transplant is for patients with blood cancers like leukemia or lymphoma. Researchers want t…

This study is testing a new treatment plan for men with high-risk prostate cancer. It combines a shorter-than-usual course of hormone-blocking drugs with two types of targeted radiation to the prostate and pelvis. The goal is to see if this approach is safe and effective at keepi…

This study is comparing two methods of delivering heated chemotherapy directly into the abdomen after surgery for appendix or colorectal cancer that has spread there. About 292 patients will be randomly assigned to receive either chemotherapy right after surgery or a heated versi…

This study is testing whether the drug AG-120 is safe and effective for people with advanced or returning chondrosarcoma, a type of bone cancer, that has a specific genetic change called an IDH1 mutation. The main goal is to see if the drug can stop the cancer from growing. The t…

This study is testing if a laser procedure can safely treat very small thyroid cancers as an alternative to surgery. It will involve 10 patients who have a tiny papillary thyroid cancer but do not want to just watch and wait. Doctors will use a needle to guide a laser to heat and…

This study is testing a new, more stable version of a standard chemotherapy drug called melphalan. The goal is to see if this new formulation can be dosed more precisely and might cause fewer side effects like kidney or heart damage. It is for adults with multiple myeloma or AL a…

This study is testing if giving men with high-risk or early-spreading prostate cancer a combination of hormone-blocking drugs for several months before surgery can shrink the cancer as much as possible. The goal is to control the disease better and lower the chance of it coming b…

This study is testing if adjusting the dose of a drug called rabbit ATG based on a patient's individual needs can help the immune system recover faster after a stem cell transplant. The goal is to reduce serious side effects and improve survival for children and adults with certa…

This study is testing if adding an immunotherapy drug called nivolumab to a standard re-treatment of radiation and the drug bevacizumab can help people with glioblastoma that has come back. It aims to see if this three-part combination helps patients live longer and keeps the can…

This study is testing if adding a radioactive drug called radium-223 to a type of targeted radiation (SBRT) works better than the radiation alone. It's for men whose prostate cancer has spread to only a few spots in their bones but is not yet resistant to hormone therapy. The goa…

This study is testing whether a combination of an antibody called Hu3F8 and a drug called GM-CSF can help keep patients with recurrent osteosarcoma (a type of bone cancer) in remission longer and prevent the cancer from returning. The trial involves 46 participants aged 1 to 40 w…

This study is testing if a drug called anakinra can prevent or reduce severe brain-related side effects and dangerous immune reactions in adults receiving CAR-T cell therapy for certain B-cell cancers. The goal is to make this powerful cancer treatment safer by controlling its mo…

This large, late-stage trial is testing if adding a radioactive drug called Radium-223 to standard chemotherapy (docetaxel) helps men with advanced prostate cancer that has spread to the bones live longer. The study enrolled 732 men to directly compare the combination treatment a…

This study is testing if a short, high-precision form of radiation (SBRT) can help restart the effectiveness of immunotherapy drugs in patients whose cancer has started to grow again. It involves adults with certain advanced cancers (like melanoma, lung, or bladder cancer) who ar…

This study is testing whether a combination of two immunotherapy drugs, etrumadenant and zimberelimab, can help control advanced dedifferentiated liposarcoma. It is for adults whose cancer has spread, returned after prior treatment, or cannot be removed by surgery. The main goal …

This study is testing whether combining three different types of drugs is a safe and effective treatment for advanced stomach and esophageal cancer that has spread. The combination aims to attack cancer by boosting the immune system, damaging cancer cell DNA, and blocking protein…

This study is testing whether the drug niraparib can help control advanced soft tissue or uterine sarcoma that has specific mutations in DNA repair genes. It is for adults whose cancer has worsened after at least one prior treatment. The main goals are to see if the drug can dela…

This study is testing if adding two oral medications, lenalidomide and CC-486, to standard radiation therapy is safe and effective for treating plasmacytoma, a type of bone tumor related to multiple myeloma. It aims to see if this combination can better control the disease. The t…

This study is testing whether two immunotherapy drugs, durvalumab and tremelimumab, can help control germ cell tumors that have returned or stopped responding to standard treatments. The trial is enrolling 30 adults whose cancers have progressed after at least one prior therapy. …

This early-stage study is testing whether giving a short course of radiation therapy before standard CAR-T cell treatment is safe and practical for people with B-cell lymphoma that has returned or not responded to other treatments. The goal is to see if this combined approach hel…

This is a small pilot study to see if meclofenamate, a drug previously used for pain, can help control cancer that has spread to the brain (brain metastases). The study will involve about 30 adults whose brain metastases have returned or worsened. The main goal is to see if it's …

This study is testing whether combining four medications—daratumumab, carfilzomib, lenalidomide, and dexamethasone—is safe and effective for people newly diagnosed with multiple myeloma, a cancer of plasma cells in the bone marrow. The main goal is to see if this combination can …

This study is testing if giving a second dose of a personalized immune cell therapy (tisagenlecleucel) early can help keep leukemia from coming back in children and young adults. It focuses on patients whose cancer returned or didn't respond to other treatments and who are alread…

This study tests whether adding an experimental drug called PEGPH20 to standard chemotherapy helps control advanced pancreatic cancer. PEGPH20 works by breaking down a substance called hyaluronan that pancreatic tumors produce, which may help shrink tumors. The research involves …

This study is testing whether adding the drug thalidomide to the standard drug ruxolitinib works better for people with myelofibrosis, a rare bone marrow cancer. It aims to see if the combination can shrink the cancer and improve problems like anemia, enlarged spleen, and other s…

This study is testing whether using a precise, high-dose radiation treatment on a few new or growing tumors can help people with advanced lung or breast cancer stay on their current medications longer. It aims to see if this approach can delay the cancer from getting worse. The t…

This study tested whether adding the drug cetuximab to standard chemotherapy could better shrink advanced thymoma or thymic carcinoma tumors before surgery. It involved 18 patients with these rare cancers that had not spread to distant organs. The goal was to see if this combinat…

This study is testing whether adding two new immunotherapy drugs, durvalumab and tremelimumab, to standard chemotherapy and radiation is safe and effective for treating esophageal and gastroesophageal junction cancer. The trial involves 64 patients who will receive the drug combi…

This trial is testing a new treatment for advanced cancers that have spread to the lining of the chest (pleura), including mesothelioma, lung cancer, and breast cancer. Doctors collect a patient's own immune cells (T cells), genetically modify them to recognize a cancer protein c…

This study is testing whether combining a targeted radiation drug (177Lu-girentuximab) with an immunotherapy drug (nivolumab) is safe and effective for treating advanced kidney cancer that has a specific protein (CAIX). It is for adults with clear cell kidney cancer that has spre…

This study is testing whether using a lower dose of radiation and targeting a smaller area after sarcoma surgery is as effective as the standard, higher-dose treatment. Researchers want to see if this approach still controls the cancer while causing fewer and less severe long-ter…

This small, early-stage study is testing whether the drug pembrolizumab can prevent cancer from returning in people who have had surgery to remove a solid tumor but still have traces of tumor DNA in their blood. The trial involves about 17 participants who will receive the drug f…

This study is testing whether a new prescription cream (ruxolitinib 1.5%) is safer and more effective than standard moisturizers for treating a specific type of skin inflammation that can occur after a stem cell transplant. About 24 participants will apply the test cream to one s…

This is an early-stage study testing the safety of a new treatment called MCARH109, a type of CAR T-cell therapy, for people with advanced multiple myeloma. The treatment involves modifying a patient's own immune cells to target and potentially stop the growth of cancer cells. Th…

This study is testing a new type of PET scan to see if it can effectively show activity in aggressive brain tumors. It involves adults with high-grade gliomas or brain metastases who are already scheduled for a biopsy or surgery. The goal is to see if this scan can provide cleare…

This study is testing a special camera that uses a safe dye to show blood flow in tissue during reconstructive surgery. It aims to help surgeons make better decisions in real-time while operating on women who need reconstruction after gynecologic cancer surgery. The goal is to se…

This study is testing whether a new type of imaging scan, called a PSMA PET scan, is more accurate than standard scans at showing how prostate cancer responds to treatment. Researchers will follow 58 men with progressive prostate cancer. The goal is to see if changes on these spe…

This study is testing a new imaging method to help surgeons find the first lymph node where vulvar cancer might spread. It compares a new light-based dye to the current standard radioactive dye in 22 patients with early-stage cancer. The goal is to see if the new method is as goo…

This study is testing new non-invasive imaging techniques to better examine skin lesions and normal skin. Researchers are collecting images of various skin spots along with small, targeted biopsies to compare results. The long-term goal is to develop technology that improves earl…

This study is testing whether a blood test can detect if aggressive B-cell lymphoma has returned after chemotherapy treatment. Researchers want to see if this test can predict relapse earlier than standard scans and exams. If successful, it could help patients avoid frequent imag…

This study aimed to test a new two-step PET scan method to better find cancer cells that produce a specific marker called CA19-9. It was designed for adults with certain cancers like pancreatic, bladder, or gastrointestinal tumors. The main goals were to find the safest dose and …

This study is testing whether a special MRI-guided biopsy can accurately tell when breast cancer has completely disappeared after chemotherapy. Researchers want to see if this biopsy method is reliable enough that, in the future, some women who show no cancer on their post-treatm…

This study is testing whether adding a special breath-holding MRI scan to the standard pre-surgery brain mapping process makes it more accurate. Researchers want to see if this combined approach better identifies critical brain areas involved in speech and movement, which surgeon…

This study is testing a new imaging method called MSOT to see if it can help doctors better visualize breast tumors and melanoma. Participants will have the MSOT scan right before their standard breast biopsy procedure. The goal is to see if this new technology can successfully c…

This study is testing a new, experimental radioactive tracer designed to stick to cancer cells for PET scans. The goal is to see if it can create clearer pictures of melanoma and malignant brain tumors than current scans. It involves a single, very small dose and is for research …

This study is testing whether injecting a small amount of radioactive sugar (18F-FDG) into the cervix before a PET/CT scan can create a clearer picture of which lymph nodes contain cancer. Researchers want to see if this method helps surgeons better identify and remove cancerous …

This study is testing how well a lymph node biopsy procedure works for women with advanced breast cancer who have already received chemotherapy. Researchers want to see if this less invasive test can accurately detect any remaining cancer cells after treatment. The goal is to hel…

This study is testing whether a blood test can help find HPV-related throat cancer early. Researchers are enrolling adults aged 45+ with certain sexual histories who have not had this cancer before. The goal is to see if looking for traces of HPV in the blood is a practical way t…

This study is testing a new imaging drug called PARPi-FL to see if it can help doctors get clearer pictures of head and neck cancer. It involves 12 adult patients with confirmed cancer who are scheduled for surgery at Memorial Sloan Kettering. The main goal is to check the safety…

This study is testing a new way to take pictures of cancer tumors using a special light called Cerenkov luminescence. The goal is to see if this method can clearly show tumors in areas like the neck, armpit, or groin. The study involves 102 adults with thyroid cancer or other can…

This is the first study in people to test a new fluorescent dye called PARPi-FL. The goal is to see if the dye can help surgeons better see and detect oral cancer during an operation. Researchers will first check the dye's safety at different doses in 23 patients, then see which …

This study is testing two different ways to help women who had chest radiation as children get recommended breast cancer screenings. Researchers want to see if personalized mailings and phone coaching are more effective than standard information at getting women to complete mammo…

This study is testing whether adding a special reconstruction technique during lymph node removal surgery can prevent lymphedema—a painful, chronic swelling of the arm that often occurs after breast cancer treatment. The trial involves 180 female breast cancer patients who are ha…

This small pilot study is testing whether a 12-week whole food, plant-based diet is practical and helpful for overweight people with early blood cell conditions (MGUS or smoldering myeloma) that can sometimes turn into cancer. Researchers want to see if participants can stick to …

This study is testing if a 'stool transplant' using a patient's own pre-treatment stool can prevent severe C. difficile infections after a stem cell transplant. Patients scheduled for a transplant will have a stool sample collected and frozen before treatment. After the transplan…

This study tests whether placing a supportive mesh during bladder removal surgery helps prevent hernias from developing around the stoma (opening) afterward. Researchers are comparing outcomes for 178 bladder cancer patients who receive the mesh with their surgery versus those wh…

This study tested whether a community education campaign, with or without text message reminders, could help more Mexican American parents get their children fully vaccinated against HPV. Researchers worked with about 180 parents who had unvaccinated kids aged 9-17. They compared…

This study is testing whether regular aerobic exercise can prevent cancer from returning in people who have already been treated. Researchers are working with 33 people who have had breast, prostate, or colorectal cancer to find the right amount of weekly exercise that safely low…

This study is testing whether it's practical to offer a smartphone app with mindfulness exercises to lung cancer patients before and after their surgery. The goal is to see if using the app helps reduce anxiety and distress related to their cancer diagnosis and treatment. The sma…

This study is testing whether acupuncture can help reduce nighttime urination (nocturia) in men who have survived prostate cancer. Researchers want to see if acupuncture is a practical treatment option that can also improve related symptoms like poor sleep, hot flashes, fatigue, …

This study is testing whether adding personalized supportive care (palliative care) to early-stage cancer drug trials helps patients. It involves 83 adults with advanced solid tumors who are starting a Phase I trial. Researchers want to see if this extra support makes it easier f…

This study is testing whether it is safe and practical for breast cancer survivors to take a medication called flibanserin while they are on their standard hormone therapy (tamoxifen or similar drugs). The researchers want to see if flibanserin can help improve low sexual desire,…

This small pilot study is testing whether a special support program is practical and helpful for women with advanced ovarian cancer. The program includes exercise, nutrition, and stress management, and is given alongside chemotherapy before major surgery. The goal is to see if th…

This study aims to see if two specific types of acupuncture work better than usual medical care for reducing chronic pain. It involves 360 adults, primarily cancer survivors, who have had musculoskeletal pain for at least three months. Participants are assigned to receive either …

This study is testing whether a pill form of minoxidil can safely help regrow hair in children and young adults who have persistent hair loss after finishing cancer treatment. It will involve about 10 participants aged 6 to 18 who completed cancer therapy at least a year ago. Res…

This study is testing whether pancreatic enzyme replacement therapy (PERT) can help people with advanced pancreatic cancer maintain their body weight while on chemotherapy. Researchers are comparing two different dosing schedules of the enzyme supplement pancrelipase. The main go…

This study is testing whether a type of talk therapy called behavioral activation can be delivered effectively by phone or video to treat depression in older adults who have survived cancer. Researchers are working with 86 participants aged 65+ who have a history of cancer and ar…

This study is developing and testing a mobile app program to help breast and rare cancer survivors manage the fear of their cancer returning. Researchers are working with 252 survivors to create and refine different versions of the app, checking if they are easy to use and helpfu…

This study aims to find out whether acupuncture or massage provides better long-term pain relief for people with advanced cancer. Researchers will follow 300 patients over 26 weeks to see which approach helps more with pain and improves quality of life. The trial focuses on peopl…

This study is testing whether giving methadone during complex spinal surgery for cancer patients leads to better pain control in the first three days after the operation. Researchers want to see if this approach reduces how much additional opioid pain medication patients need aft…

This study is testing whether a game-based exercise plan can help childhood cancer survivors become more physically active. The program involves both the survivor and a parent working together as a team. Researchers want to see if this approach increases daily activity and improv…

This study is adapting a counseling therapy called 'Meaning-Centered Psychotherapy' to better meet the cultural and language needs of Chinese immigrant cancer patients. The goal is to help patients cope with the emotional burden of advanced cancer by finding a sense of purpose an…

This study compares two common surgeries used when cancer spreads to and weakens the thigh bone, causing fractures. Researchers want to know which procedure helps patients move better, feel less pain, and enjoy better quality of life after surgery. The study involves 73 adults wi…

This small, early-stage study is testing whether a procedure called a fecal microbiota transplant (FMT) can safely help reduce severe diarrhea caused by cancer immunotherapy drugs. The treatment involves transferring stool from a healthy donor into a patient's intestine during a …

This study is testing whether mindfulness training can help reduce chronic pain in people with cancer. Researchers are comparing a mindfulness program called MORE against a waitlist control group in 76 participants. The goal is to see if teaching people to focus on the present mo…

This study is testing whether adding acupuncture to standard pain care can help patients with multiple myeloma or lymphoma use fewer opioid medications during high-dose chemotherapy. Researchers are comparing two groups: one receiving acupuncture plus usual care, and one receivin…

This study is testing if a drug called siltuximab can reduce the severe fatigue, pain, and nausea that often follow a stem cell transplant. It focuses on patients aged 60-75 with multiple myeloma or AL amyloidosis. The goal is to block a specific protein linked to inflammation, a…

This study is training visiting nurses to provide a special type of talk therapy focused on finding meaning to homebound cancer patients. The goal is to see if this brief therapy, delivered by nurses during regular home visits, can help patients cope with the emotional and psycho…

This study is testing a phone-based program designed to help patients with advanced cancer and their caregivers. The program focuses on improving communication, managing difficult emotions, and reducing caregiver stress. It offers a culturally tailored version for Latino/a partic…

This study is testing whether a medication called sucralfate can prevent or reduce painful swallowing (radiation esophagitis) in lung cancer patients receiving chest radiation. It will enroll 142 adults to see if the drug helps patients avoid needing strong opioid painkillers. Th…

This study is testing whether a 5-week computer training program can help breast cancer survivors who are having memory and attention problems after chemotherapy. Researchers want to see if using special memory-training software can improve these cognitive issues. The study will …

This study is testing whether a special type of talk therapy, called poetic dignity therapy, is practical and helpful for LGBTQ+ cancer patients receiving palliative care. The therapy helps patients tell their life stories and create a meaningful legacy document to share with lov…

This study is testing whether using a deeper level of muscle relaxation during robotic prostate cancer surgery leads to less pain after the operation. Researchers are comparing this deeper relaxation to the standard moderate level in about 140 men having this surgery. The goal is…

This study tested two different types of support groups for women who have finished treatment for early-stage breast cancer. One group focused on finding meaning and purpose after cancer, while the other was a general discussion group for mutual support. The research aimed to see…

This study aims to improve the experience for lymphoma survivors by training their doctors in better communication skills. It involves 314 patients with Hodgkin's or Diffuse Large B-cell Lymphoma who have finished curative treatment and are in remission. The research will measure…

This study is testing if a guided pelvic floor muscle exercise program, taught by a physical therapist before and after prostate removal surgery, is practical and acceptable for patients. Researchers will see how many people join and stick with the program, and ask participants a…

This study is testing whether adding an interactive 3D visualization tool to a standard surgical consultation helps breast cancer patients feel more satisfied with the information they receive about reconstruction options. Researchers want to see if women who use the 3D tool are …

This study aims to understand how different antibiotics affect the community of helpful bacteria in the gut of stem cell transplant patients. Researchers are comparing two common antibiotic treatments given when patients develop fever with low white blood cell counts. The goal is…

This study aims to understand how regular exercise might change the biology of breast tumors. Researchers are comparing women with early-stage breast cancer who are either very active or mostly sedentary. They will analyze tumor tissue from surgery to look for differences in gene…

This study aims to combine information from PET/MRI scans with blood and tissue tests to create detailed profiles of high-grade serous ovarian cancer. Researchers will use computer analysis to examine imaging results alongside genetic and immune system data from tumor samples. Th…

This study aims to understand how proton beam radiation therapy for brain tumors affects brain connections, thinking skills, and quality of life in children and young adults (ages 6-25). Researchers will use special brain scans and thinking tests to compare patients who received …

This study aims to learn more about how basal cell carcinoma (BCC), a common type of skin cancer, grows over time. It will not provide any treatment to participants. Instead, researchers will closely monitor small, untreated BCCs in 26 adults for three years using special imaging…

This study aims to learn more about how prostate cancer changes after radiation treatment by using advanced MRI scans. Researchers will scan 120 men with prostate cancer before and after their radiation therapy. The goal is to see if these detailed pictures can help doctors bette…

This study collects normal and cancerous tissue, blood, and fluid samples from men with various prostate conditions. Researchers will analyze these samples to understand why some people get prostate cancer, why some cancers are more aggressive, and why treatments work differently…

This study aims to create a better tool for predicting how long patients with cancer that has spread to their bones might live. Researchers are combining doctors' assessments with patients' own reports about their health to improve survival estimates. The goal is to help patients…

This study aims to understand how satisfied patients are with their appearance and scar results after skin cancer surgery, and how it affects their quality of life. Researchers are inviting 3,000 adults who have had surgery for skin cancer to complete a one-time online survey. Th…

This study aims to understand the genetic causes of cancer that run in families. Researchers are collecting blood or saliva samples from patients with certain cancers and their relatives to build a DNA bank. The goal is to identify genetic patterns that increase cancer risk, whic…

This study is creating a large registry to learn more about urinary tract cancers like bladder cancer. Researchers are collecting health information and saliva samples from over 3,500 people, including those with cancer and those without, to look for genetic markers and other ris…

This study aims to understand the experiences and needs of parents who have lost a child to cancer. Researchers interviewed 160 parents to learn about their grief journey and how they find meaning after loss. The information will help develop better support programs to help paren…

This study aims to understand how breast cancer treatments affect menstrual cycles and quality of life in young women. Researchers are following 810 women aged 45 and younger who have been recently diagnosed with breast cancer. The goal is to learn how often treatment causes earl…

This study aims to find new markers in blood and imaging scans that could help doctors better detect colon cancer and predict its likelihood of spreading to the liver. It involves 51 adults who are already scheduled for colon cancer surgery. The research focuses on gathering info…

This study aims to understand how the cancer drug tucatinib reaches brain tumors in patients whose breast cancer has spread to the brain. Researchers will examine tumor tissue from 9 patients who are already scheduled for brain surgery to see how the drug is absorbed and why some…

This study aims to create better rules for doctors to use when reading PET scans of patients with neuroendocrine tumors. Researchers will test if these new rules can more accurately predict whether a patient's cancer will get better, worse, or stay the same after treatment. They …

This study aims to better understand the conversations between lung cancer patients and their doctors. Researchers are observing these consultations and asking patients about their experience to see how communication quality affects patient satisfaction and well-being. The study …

This study aims to understand why some people with BRCA or PALB2 gene mutations develop pancreatic cancer. Researchers are creating a registry (a database) of 600 people, including those with pancreatic cancer who carry these mutations, their relatives, and control groups. The go…

This is the first time researchers are testing a new experimental imaging tracer called F-Glutamine in people. The study aims to see how long the tracer stays in the blood and where it goes in the body after injection. If successful, future studies will test if scans using this t…

This study is testing whether special types of MRI scans taken before and during treatment can predict how well patients with head and neck cancer will respond to therapy. Researchers are looking at 272 patients to see if these advanced scans can identify which patients are likel…

This study aims to learn more about how specific inherited gene changes are linked to cancer risk. It enrolls people who have these gene changes, as well as their family members, to track their health over time. The goal is to gather information that helps doctors give better adv…

This early study aims to understand how a new drug called PUH71 moves through the body and gathers in tumors when given in very small amounts. Researchers will use PET scans to track the drug in patients with various cancers, including lymphoma, myeloma, and solid tumors. The res…

This study aims to understand how breast cancer treatment affects quality of life differently in women of various ages. Researchers will follow 650 women for 18 months after diagnosis, collecting information through questionnaires about their physical and emotional well-being. Th…

This is a very early study to test a new type of imaging tracer for brain tumors. Researchers are giving a tiny, safe dose of the tracer to a small group of patients and using PET scans to see how it moves through the body and collects in the tumor. The goal is to gather informat…

This study aims to learn more about how well immunotherapy works for people with sarcoma. Researchers will collect information from the medical records of about 250 patients who have received certain immunotherapy treatments at Memorial Sloan Kettering Cancer Center. The goal is …

This study aims to understand why some prostate cancer survivors experience memory and thinking problems, often called 'chemo brain' or 'cancer-related cognitive dysfunction.' Researchers are collecting information from 200 survivors to explore connections with anxiety, depressio…

This study aims to understand why some bone cancers and solid tumors stop responding to chemotherapy drugs. Researchers will analyze tumor samples and blood from patients who have had surgery or biopsy to identify biological factors linked to treatment resistance. The goal is to …

This study aims to learn more about how COVID-19 infections affect people with cancer and their household members. Researchers are collecting information through online surveys about medical history, lifestyle, and risk factors. The goal is to build a database to understand the i…

This study is testing whether regular brain scans and spinal fluid tests can detect the early spread of breast cancer to the brain in people with HER2-positive breast cancer. Researchers want to see if finding this spread early, before symptoms start, is possible and practical. T…

This study aims to understand the long-term health and quality of life of adults who survived retinoblastoma, a childhood eye cancer. Researchers are surveying over 470 survivors to learn about their physical health, emotional well-being, and daily life years after treatment. The…

This study aims to test and improve new MRI scanning and analysis techniques. Researchers will scan healthy volunteers to see if new methods produce clearer images and help doctors feel more confident in their diagnoses. The goal is to gather information to improve MRI technology…

This study is training cancer care providers in a special type of talk therapy called Meaning-Centered Psychotherapy (MCP). The goal is to teach clinicians how to help their patients cope with cancer by finding meaning and purpose. Researchers will measure how well the 350 partic…

This study aims to understand how doctors communicate with patients who have glioblastoma, a serious brain cancer, and their caregivers. Researchers are observing conversations about scan results, treatment options, and difficult topics like prognosis and end-of-life care. The go…

This study aims to understand how breast cancer treatments like chemotherapy might affect long-term memory and thinking skills in older survivors. Researchers are comparing nearly 500 older women who are breast cancer survivors to women who have never had cancer, tracking their c…

This study aims to understand how surviving a childhood brain tumor affects long-term thinking, memory, and behavior. Researchers are comparing brain scans and thinking tests from 42 survivors to those of healthy children. The goal is to identify biological reasons for any lastin…

This study aims to understand how much oxygen women with HER2-positive breast cancer use during exercise when they have mild heart issues from their cancer treatment. Researchers want to see if this exercise test can predict how well participants' hearts and lungs will work if th…

This study aims to understand why some ovarian cancers become resistant to initial treatment. Researchers will examine 10 patients with advanced ovarian cancer who undergo a follow-up surgical procedure after completing chemotherapy. The study will compare outcomes between patien…

This study aims to learn if tooth enamel loss is more common in people with certain cancers, like stomach or esophageal cancer. Researchers will take pictures of participants' teeth to look for signs of erosion. The goal is to see if this simple check could one day help doctors d…

This study is testing a new type of PET scan to see if it can show how much of a standard chemotherapy drug actually gets into pancreatic tumors. Researchers will scan about 30 patients with pancreatic cancer before they start treatment. The goal is to gather information that cou…

This study aims to find out how common poor leg circulation (peripheral arterial disease or PAD) is in older cancer patients who have risk factors like diabetes or smoking. Researchers are checking 114 patients aged 65+ before major cancer surgery to see if they have PAD, which i…

This study aims to understand how often and why women with non-metastatic breast cancer experience hair loss, skin aging, and nail changes during chemotherapy or hormone therapy. Researchers are following over 500 women to identify who is most at risk and how these side effects i…

This study is testing whether it's practical to use a new communication tool with breast surgery patients. The tool shows patients their own scores on surveys about pain, movement, and wellbeing after surgery and suggests topics to discuss with their doctor. Researchers want to s…

This study is testing whether a very low-carbohydrate (ketogenic) diet is safe and tolerable for overweight or obese patients newly diagnosed with endometrial (uterine) cancer before they have surgery. Researchers want to see if patients can stick to the diet and what effects it …

This study aims to understand how the appearance of normal breast tissue on MRI scans might relate to a woman's risk of developing breast cancer. Researchers are comparing MRI and mammogram images from over 2,000 women—some recently diagnosed with breast cancer and others at high…

This study aims to understand if radiation therapy for head and neck cancer affects memory, focus, and other thinking skills. Researchers will follow 54 recently diagnosed patients for one year, asking them to complete thinking tests and questionnaires at three different times. T…

This study is testing a new online brain game to measure thinking and memory changes in breast cancer survivors. Researchers want to see if this computer test works as well as traditional clinic visits for tracking 'chemo brain' or other thinking problems. The goal is to help doc…

This study collects leftover tissue and blood samples from patients with various cancers to help researchers understand these diseases better. The samples come from patients already having medical procedures, using only material that would otherwise be discarded. Researchers will…

This study aims to understand if the bacteria living in our gut and our diet affect cancer risk in people with inherited conditions that make them prone to colon cancer. Researchers are collecting stool samples, colon tissue from routine colonoscopies, and diet questionnaires fro…

This study is tracking people with multiple hazy spots on their lung scans called ground glass opacities (GGOs). Researchers are monitoring 338 participants over time to learn when these spots might turn into lung cancer and when treatment should begin. The goal is to gather info…

This study aims to gather basic information about how a special imaging agent, called [13C]pyruvate, behaves in the bodies of healthy volunteers during an MRI scan. Researchers want to see how this agent is distributed and used for energy in different organs to create a normal re…

This study aims to understand if common hormone therapies for prostate cancer affect memory, concentration, and daily functioning in men aged 65 and older. Researchers will compare the thinking skills of men starting therapy, men already on it, and men not on it. The goal is to g…

This study aims to understand how cisplatin chemotherapy might damage blood vessels, which could explain why some patients develop heart problems years later. Researchers will compare blood vessel function in two groups of men with germ cell cancer: those receiving cisplatin and …

This study aims to understand how two different treatments for childhood eye cancer (retinoblastoma) affect survivors' long-term quality of life. Researchers are comparing children who had their eye removed with those who received chemotherapy directly into the eye's artery to sa…

This study aims to understand if people with Lynch Syndrome, a genetic condition that increases cancer risk, follow through with the recommended screening tests for multiple organs after receiving genetic counseling. Researchers are observing over 1,500 adults who have received t…

This study is testing new ways to perform MRI scans to prevent blurry images caused by patient movement. Researchers are comparing new scanning techniques and computer processing methods to the standard ones currently used. The goal is to see if these new approaches are practical…

This study aims to understand how cancer affects the identity, relationships, and emotional needs of young survivors. Researchers are interviewing 300 survivors aged 15-25 who finished treatment at least 6 months ago. The goal is to use this information to provide better care and…

This study aims to better understand the anxiety men feel about using penile injection therapy to treat erectile dysfunction after major pelvic surgery for cancer. Researchers are following 126 men through their injection training and for four months afterward, asking them to com…

This study aims to learn how to offer BRCA gene testing to a larger number of people and make it a regular part of healthcare. It involves over 5,400 adults of Ashkenazi Jewish ancestry who have not had this genetic test before. The research focuses on how people decide to get te…

This study aims to create detailed health registries for non-communicable diseases (like cancer, diabetes, and heart disease) across sub-Saharan Africa. It will enroll nearly 7,000 people, including both patients and healthy volunteers for comparison. The goal is to gather accura…

This study aims to understand how a lab-made antibody called Hu3F8 moves through the body and reaches tumors in patients with certain advanced cancers. Researchers will use a special PET scan to track a tiny radioactive tag attached to the antibody. The goal is to gather informat…

This study collects blood, saliva, and tissue samples from breast cancer patients and healthy volunteers to create a research bank. Researchers at Memorial Sloan Kettering will use these samples to study what causes breast cancer and find better ways to prevent, detect, and treat…

This study aims to understand why some patients with relapsed multiple myeloma don't receive advanced cellular therapies like CAR-T treatments or stem cell transplants. Researchers will follow 49 patients and their doctors to track referral patterns and treatment decisions. The g…

This study aims to develop a better way to predict whether liver cancer ablation treatments are working. Researchers will analyze tissue samples from treated tumors to see if they can tell the difference between cancer cells and healthy cells that just look different after treatm…

This study is testing a new training program for nurses called PACT. The goal is to see if it helps nurses better support family members who are caring for loved ones with advanced gastrointestinal cancer in the hospital. Researchers will observe how often nurses use these new sk…

This study aims to discover new types of inherited gene changes that might explain why some people develop cancer. Researchers are studying cancer patients along with their unaffected parents to look for gene differences that appear in the child but not the parents. The goal is t…

This study is testing a different way to provide genetic testing to cancer patients. Instead of referring patients to a genetic counselor, doctors themselves order the tests, and counselors then give results by phone. Researchers are measuring how this change affects patient dist…

This study aims to find a safe and practical amount of exercise for people to do at home before cancer surgery. It will test different exercise plans using smartphone apps and wearable devices to see what works best. The main goal is to learn if this approach is feasible and how …

This study tests a training program for nurses and social workers at a cancer hospital to help them better support family caregivers. The program teaches staff how to communicate more effectively and compassionately with families facing the challenges of cancer care. Researchers …

This study is testing a new set of brain function tests called the SAE Battery to understand how breast cancer treatment affects thinking, attention, and emotion processing. Researchers are comparing 187 breast cancer patients with healthy women to see if treatment changes how th…