Electric fields could prime immune system against lung cancer
NCT ID NCT05764954
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing whether a device that delivers electric fields (TTFields) to lung tumors is safe and practical when used for 3 weeks before surgery. The study includes 12 people with early-stage lung adenocarcinoma. Researchers also want to see if this treatment can boost the body's immune response against the cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tumor-Treating Fields (TTFields) via the NovoTTF-200T System
- What this could lead to
- If it works, this could point toward a new way to help the immune system fight lung cancer before surgery, potentially improving outcomes.
- What could go wrong
- This is a very early, small phase 1 trial with only 12 participants, so results may not apply widely. The device must be worn 18 hours daily for 3 weeks, which may be burdensome, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
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Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Suffolk - Commack (Consent Only)
Commack, New York, 11725, United States
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Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, 10604, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Electric current test may forecast lung surgery complications
- Blood test could reveal how lung cancer evolves during treatment
- AI reads CT scans to predict which lung nodules turn cancerous
- CRISPR Gene-Edited immune cells aim to fight lung cancer – but trial never started
- Cancer-Fighting super cells tested in solid tumors – study halted early
- Simple blood and tissue tests could revolutionize lung cancer care