New drug combo may help bladder cancer patients avoid surgery

NCT ID NCT03504163

First seen Nov 06, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tests whether combining two immunotherapy drugs—pembrolizumab and BCG—can keep high-risk T1 bladder cancer from coming back. About 45 participants will receive this combination as their first treatment, with the goal of avoiding the need for bladder removal surgery. The main measure of success is how many patients remain cancer-free at 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    Basking Ridge, New Jersey, 10065, United States

  • Memorial Sloan Kettering Bergen (All protocol activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (All protocol activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering West Harrison (All Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.