Can a precise radiation burst stall Cancer's spread?

NCT ID NCT03808662

Ongoing Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving stereotactic body radiotherapy (SBRT) to growing metastatic tumors can delay overall cancer progression. About 107 adults with triple-negative breast cancer or non-small cell lung cancer that has started to grow in a few spots will receive SBRT or no immediate radiation. The goal is to see if early, precise radiation can buy more time before the disease gets worse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic body radiotherapy (SBRT)
What this could lead to: If it works, this could give patients more time before their cancer progresses, potentially delaying the need for stronger treatments.
What could go wrong: This is a mid-stage trial with only 107 participants, so results may not apply to everyone. SBRT can cause side effects like fatigue or damage to nearby organs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer non-small cell lung carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER NON-SMALL CELL LUNG CANCER METASTATIC NSCLC NSCLC STAGE IV NSCLC STAGE IV WITHOUT EGFR/ALK MUTATION TNBC - TRIPLE-NEGATIVE BREAST CANCER TRIPLE NEGATIVE BREAST CANCER

Contacts and locations

Locations

Fred Hutchinson Cancer Research Center (Data Analysis Only)

Seattle, Washington, 98109, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Rockville Centre

Rockville Centre, New York, 11570, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Princess Margaret Hospital/Ontario Cancer Institute (Data Analysis Only)

Toronto, Ontario, Canada

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