Could a prostate cancer drug help fight a tough breast cancer?

NCT ID NCT02750358

Ongoing Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking enzalutamide for one year after standard treatment is practical for people with early-stage triple negative breast cancer that has androgen receptors. About 50 participants will take the drug and report on their quality of life. The main goal is to see how many can stick with the full year of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: enzalutamide
What this could lead to: If it works, this could point toward a new treatment option for a hard-to-treat breast cancer subtype.
What could go wrong: This is a small, early-phase feasibility study, not a large efficacy trial. It may not show clear benefit, and side effects could limit how many patients can complete the full year of treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER EARLY STAGE TRIPLE NEGATIVE BREAST CANCER

Contacts and locations

Locations

Coney Island Hospital

Brooklyn, New York, 11235, United States
Hartford Healthcare Cancer Institute @ Hartford Hospital

Hartford, Connecticut, 06102, United States
Kings County Hopsital Center

Brooklyn, New York, 11203, United States
Lehigh Valley Health Network

Allentown, Pennsylvania, 18103, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Queens Hospital Center

Jamaica, New York, 11432, United States
Woodhull Hospital

Brooklyn, New York, United States

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