New combo therapy targets hard-to-treat liposarcoma

NCT ID NCT05886634

Ongoing Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining two drugs—etrumadenant and zimberelimab—can shrink or slow advanced dedifferentiated liposarcoma that has returned, spread, or can't be removed by surgery. About 16 adults with this rare cancer will receive the treatment. The goal is to see how many patients respond within 24 weeks.

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Conditions

The condition(s) this trial relates to.

dedifferentiated liposarcoma liposarcoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEDIFFERENTIATED LIPOSARCOMA METASTATIC DEDIFFERENTIATED LIPOSARCOMA RECURRENT DEDIFFERENTIATED LIPOSARCOMA SARCOMA SARCOMA,SOFT TISSUE SOFT TISSUE SARCOMA UNRESECTABLE DEDIFFERENTIATED LIPOSARCOMA

Contacts and locations

Locations

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited protocol activities)

Rockville Centre, New York, 11553, United States
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)

Harrison, New York, 10604, United States
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)

Basking Ridge, New Jersey, 07920, United States

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