Can a shorter chemo combo tame High-Risk neuroblastoma?
NCT ID NCT04947501
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This pilot study is testing a new, shortened chemotherapy regimen called N9 for children with high-risk neuroblastoma, a type of cancer. The regimen combines several chemotherapy drugs given in different cycles to see if it is safe and effective. The study includes children under 19 years old with high-risk neuroblastoma who have had no more than one prior cycle of chemotherapy. The goal is to assess the safety and potential effectiveness of this approach.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A combination of chemotherapy drugs: cyclophosphamide, topotecan, vincristine, ifosfamide, carboplatin, etoposide, and doxorubicin
- What this could lead to
- If successful, this shortened chemotherapy approach could become a safer and more effective way to treat high-risk neuroblastoma in children, potentially improving outcomes.
- What could go wrong
- This is an early-phase pilot study with a small number of participants, so results may not be conclusive. Chemotherapy carries risks of side effects, and the regimen may not prove more effective than standard treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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