New drug combo offers hope for Tough-to-Treat lymphoma

NCT ID NCT06192888

First seen Jan 23, 2026 · Last updated Apr 28, 2026 · Updated 16 times

Summary

This study tests whether combining two drugs, glofitamab and lenalidomide, can help people with mantle cell lymphoma that has returned or stopped responding to prior treatments, including a BTK inhibitor. About 39 adults will take part. The goal is to see if the treatment is feasible and effective, while managing side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute (Data Collection and Specimen Analysis)

    Boston, Massachusetts, 02115, United States

  • Mayo Clinic (Data Collection Only)

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center at Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Monmouth (Limited protocol activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All protocol activities)

    Rockville Centre, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited protocol activities)

    Harrison, New York, 10604, United States

  • Washington University (Data Collection Only)

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.