Water pill could boost liver cancer treatment
NCT ID NCT03107416
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests whether adding a common water pill (bumetanide) to a standard procedure that blocks blood flow to liver tumors is safe and might help slow tumor growth. About 30 people with liver cancer that cannot be removed by surgery will take part. The study will first find the safest dose of bumetanide, then check how well it controls the tumor over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- bumetanide (a water pill) given directly into the liver artery during a standard procedure to block blood flow to the tumor
- What this could lead to
- If it works, this could point toward a new way to improve standard embolization for liver cancer, potentially slowing tumor growth.
- What could go wrong
- This is a very early, small trial (30 people) focused on safety and finding the right dose. It may not show a clear benefit, and the added drug could cause unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Basking Ridge (Consent and follow-up only)
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen (Consent and follow-up only)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Monmouth (Consent and follow-up only)
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Westchester (Consent and follow-up only)
Harrison, New York, 10604, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Immunotherapy combo tested against untreatable liver cancer
- Liver cancer drug combo shows promise in large trial
- New hope for liver cancer patients with cirrhosis? tiny trial tests drug duo
- New radioactive beads aim to outperform standard liver cancer therapy
- New drug combo shows promise for untreatable liver tumors
- New combo therapy shows promise for untreatable liver cancer