New study tests whether extra material in breast reconstruction is worth it

NCT ID NCT05316324

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two methods of prepectoral breast reconstruction after mastectomy for breast cancer: one using acellular dermal matrix (ADM) and one without. The goal is to see if using ADM leads to fewer major complications like infection or implant removal within 90 days. About 353 women aged 21-60 are taking part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acellular dermal matrix (ADM)

What this could lead to

If successful, this study could show that using ADM in breast reconstruction does not reduce complications, potentially simplifying the procedure and reducing costs.

What could go wrong

This is a single-center trial, and results may not apply to all patients or surgical techniques. The study only looks at short-term complications, not long-term outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Rockville Centre, New York, 11553, United States