New chemo cocktail shows promise against aggressive childhood cancer

NCT ID NCT00077285

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a combination of two chemotherapy drugs, irinotecan and carboplatin, as the first treatment for children and adults newly diagnosed with intermediate- or high-risk rhabdomyosarcoma, a type of muscle cancer. The goal was to see if this drug pair could shrink tumors and be given safely before standard therapy. The trial enrolled 65 participants and focused on response rates, side effects, and local tumor control.

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Conditions

The condition(s) this trial relates to.

ectomesenchymoma Malignant mesenchymal tumor rhabdomyosarcoma sarcoma undifferentiated (embryonal) sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States