Engineered t cells take aim at Hard-to-Treat leukemia

NCT ID NCT01044069

First seen May 04, 2026 · Last updated Jun 18, 2026 · Updated 9 times

Summary

This early-stage study tests a new approach for adults with B-cell acute lymphoblastic leukemia (B-ALL) that has returned or not responded to standard treatment. Researchers take a patient's own T cells, modify them in the lab to recognize and attack leukemia cells, and infuse them back after chemotherapy. The main goal is to check safety and find the right dose, while also seeing if the treatment can reduce or control the leukemia.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia B-cell acute lymphoblastic leukemia leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.