Hidden gene changes could reveal who gets cancer
NCT ID NCT00996710
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study searches for new gene changes (mutations) that appear in cancer patients but not in their healthy parents. By comparing DNA from 1,275 people with certain cancers and their families, researchers hope to find genetic clues that increase cancer risk. The goal is to better understand how these new mutations contribute to cancer and potentially identify people at higher risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify people at higher risk for certain cancers by detecting new gene changes that are not inherited.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to immediate clinical changes, and findings may not apply to all cancer types or populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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