Chemo's hidden heart risk: study probes Cisplatin's effect on blood vessels
NCT ID NCT01453660
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study looks at how the chemotherapy drug cisplatin affects the inner lining of blood vessels (the endothelium) in men with germ cell tumors. Researchers will measure blood vessel function in patients receiving cisplatin and compare them to a group who had surgery only. The goal is to better understand the link between cisplatin and long-term heart disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Cisplatin chemotherapy
- What this could lead to
- If successful, this study could help explain how cisplatin causes long-term heart problems and point to ways to prevent them.
- What could go wrong
- This is a small, early pilot study that only measures short-term changes. It may not prove a clear link or lead to any new treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.