Poop pills or procedure? fecal transplants tested for immunotherapy side effect
NCT ID NCT04883762
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether fecal microbiota transplantation (FMT) can safely reduce severe diarrhea caused by immune checkpoint inhibitors (ICIs) in cancer patients. Four adults who have persistent diarrhea despite steroids or other medications will receive a stool preparation from a healthy donor via colonoscopy. The goal is to see if the healthy bacteria can restore gut health and ease symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fecal microbiota transplantation (FMT) from a healthy donor
What this could lead to
If it works, this could offer a new way to manage severe diarrhea caused by cancer immunotherapy, helping patients stay on their cancer treatment.
What could go wrong
This is a very early, small pilot study with only 4 participants. The approach may not work for everyone, and there are risks like infection or worsening symptoms.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States