Poop pills tested to calm chemo gut woes in cancer patients

NCT ID NCT07319364

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether fecal microbiota transplantation (FMT) – taking donor gut bacteria in capsules – can prevent or reduce gastrointestinal symptoms like nausea, vomiting, and diarrhea caused by chemotherapy or targeted therapy. It involves 90 adults with advanced (Stage IV) gastrointestinal cancers who are already on treatment. Researchers will track symptom changes after FMT given before cycles 4, 6, and 8 of their cancer therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
fecal microbiota transplantation (FMT) capsules
What this could lead to
If it works, this could offer a way to reduce nausea, vomiting, and diarrhea caused by chemotherapy or targeted therapy in people with advanced gastrointestinal cancers.
What could go wrong
This is a small, early-phase (Phase 1) observational study, so results are preliminary. FMT may not work for everyone and carries risks like infection or digestive discomfort.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    RECRUITING

    Zhejiang, Hangzhou, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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