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Could a gut bacteria transplant restore hair in alopecia areata?

NCT ID NCT07705217

Not yet recruiting Disease control Sponsor: Polyclinic GrandMed Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This trial investigates whether fecal microbiota transplantation (FMT) can treat alopecia areata, an autoimmune condition causing patchy hair loss. Researchers will give adults with alopecia areata either FMT or a placebo for three days and track hair regrowth, immune changes, and gut and skin bacteria over 48 weeks. The goal is to see if restoring healthy gut bacteria can calm the immune attack on hair follicles.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
fecal microbiota transplantation (FMT) via capsules or enema
What this could lead to
If it works, this could point toward a new treatment for alopecia areata by restoring healthy gut and skin bacteria to calm the immune system and trigger hair regrowth.
What could go wrong
This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. FMT is still experimental for this condition, and its long-term safety and effectiveness are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alopecia areata

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALOPECIA AREATA FECAL MICROBIOTA TRANSPLANTATION (FMT) MICROBIOME T CELL SUBSETS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Polyclinic GrandMed

    Opatija, Croatia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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