Can exercise alter breast tumors? new study investigates

NCT ID NCT03424915

Ongoing Knowledge-focused Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how regular exercise might change the biology of breast tumors in women with early-stage breast cancer. Researchers will compare tumor and normal tissue samples from 42 women who exercise regularly versus those who don't. The goal is to understand if exercise affects tumor genetics and immune response, which could guide future research on lifestyle and cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help design future trials that test whether exercise changes breast tumor biology, potentially leading to new lifestyle-based approaches for cancer management.
What could go wrong: This is a small, observational study (42 participants) that only looks at past exercise habits, not a controlled intervention. It cannot prove cause and effect, and results may not apply to all breast cancer patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Consent and Follow-up)

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Consent and Follow-up)

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (Consent and Follow-up)

New York, New York, 10065, United States
Memorial Sloan Kettering Commack (Consent and Follow-up)

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth (Consent and Follow-up)

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Consent and Follow-up)

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester (Consent and Follow-up)

Harrison, New York, 10604, United States

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