Simple blood test could spot hidden throat cancer
NCT ID NCT05814549
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing whether a blood test called NavDx can find HPV-related oropharyngeal cancer early by looking for HPV DNA in the blood. Researchers are enrolling adults aged 45 and older with multiple sexual partners who have no history of this cancer. Participants give blood samples over time, and if the test is positive, they enter a surveillance phase to confirm the finding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- NavDx blood test
- What this could lead to
- If successful, this blood test could provide a simple way to screen for HPV-related throat cancer early, potentially catching it before symptoms appear.
- What could go wrong
- This is a very small, early feasibility study with only 9 participants, so results may not apply to the general population. The test may also miss some cancers or give false positives.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
-
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, 07645, United States
-
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
-
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, 07748, United States
-
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, 11553, United States
-
Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)
Commack, New York, 11725, United States
-
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, 10604, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood test may tailor throat cancer treatment, sparing patients from harsh side effects
- Robotic surgery may spare throat cancer patients from chemo and radiation
- Vaccine trains immune system to fight HPV-Positive head and neck tumors
- New drug combo targets HPV-Driven cancers in phase II trial
- New Vaccine-Drug combo aims to tame HPV throat cancer with less radiation
- New sedative could speed recovery for ventilator patients