Simple blood test could spot hidden throat cancer

NCT ID NCT05814549

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether a blood test called NavDx can find HPV-related oropharyngeal cancer early by looking for HPV DNA in the blood. Researchers are enrolling adults aged 45 and older with multiple sexual partners who have no history of this cancer. Participants give blood samples over time, and if the test is positive, they enter a surveillance phase to confirm the finding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NavDx blood test

What this could lead to

If successful, this blood test could provide a simple way to screen for HPV-related throat cancer early, potentially catching it before symptoms appear.

What could go wrong

This is a very small, early feasibility study with only 9 participants, so results may not apply to the general population. The test may also miss some cancers or give false positives.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

human papillomavirus-related squamous cell carcinoma oropharynx cancer oropharynx squamous cell carcinoma oropharyngeal carcinoma prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States