New sedative could speed recovery for ventilator patients

NCT ID NCT05606315

Terminated Symptom relief Sponsor: Nanfang Hospital, Southern Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests a new sedative called remimazolam for people in the ICU who need a breathing tube after oral or facial surgery. It compares remimazolam to two standard sedatives, propofol and midazolam, to see if it works just as well and helps patients wake up faster. The trial involves 117 adults and is currently on hold.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Remimazolam besylate
What this could lead to: If it works, this could offer a safer, faster-recovery sedation option for ICU patients after oral surgery.
What could go wrong: This is a small pilot trial that is currently suspended, so results are uncertain. It only tests short-term sedation, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ICU are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Mouth Neoplasms oropharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ICU REMIMAZOLAM BESYLATE SEDATION

Contacts and locations

Locations

Peking University Shenzhen Hospital

Shenzhen, Guangdong, 518036, China
Southern medical university Nanfang hospital

Guangzhou, Guangdong, 510515, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.