A single score may spot breathing trouble before it's too late in sedated children

NCT ID NCT07733544

Completed Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether a monitoring tool called the Integrated Pulmonary Index (IPI) can improve safety in children aged 2–18 who need deep sedation for procedures like lumbar puncture or bone marrow aspiration. IPI combines oxygen level, carbon dioxide, breathing rate, and heart rate into one number, aiming to catch breathing problems earlier than standard monitors. Researchers will compare how often breathing complications occur with and without IPI guidance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a sedation protocol with midazolam, fentanyl, and propofol, plus two monitoring devices (BIS and IPI)
What this could lead to: If IPI monitoring proves better at detecting breathing problems early, it could become a standard safety tool for sedating children during painful procedures.
What could go wrong: This is a small, single-center trial. IPI may not reduce complications enough to change practice, and the extra monitoring could add complexity without clear benefit.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIS INTEGRATED PULMONARY INDEX PEDIATRIC PEDIATRIC HEMATOLOGY SEDATION

Contacts and locations

Locations

Ankara Bilkent Şehir Hastanesi

Ankara, Çankaya, 06800, Turkey (Türkiye)

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