SEDATION
Clinical trials for SEDATION explained in plain language.
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New sedative tested to help ICU patients breathe on their own sooner
Disease control Recruiting nowThis study compares two sedation drugs (remazolam besylate vs dexmedetomidine) for patients who need breathing machine support in the ICU after non-cardiac surgery. It aims to see if the new drug is at least as safe and effective at helping patients wake up and breathe on their o…
Matched conditions: SEDATION
Phase: PHASE4 • Sponsor: Beijing Shijitan Hospital, Capital Medical University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Breathing breakthrough? inhaled sedation aims to get ICU patients off ventilators faster
Disease control Recruiting nowThis study is testing whether a sedation gas (isoflurane) helps critically ill patients on breathing machines get off the ventilator and out of the ICU faster than the standard IV sedation (propofol). Researchers will enroll 620 adult patients expected to need deep sedation for m…
Matched conditions: SEDATION
Phase: PHASE4 • Sponsor: Instituto de Investigación Hospital Universitario La Paz • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Calming kids before surgery: study tests two gentle breathing treatments
Symptom relief Recruiting nowThis study aims to find the best way to help children feel calm and sleepy before cleft palate surgery and prevent them from waking up agitated afterward. Researchers are comparing two inhaled (nebulized) medication combinations given before the procedure. The study involves 60 c…
Matched conditions: SEDATION
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Common numbing drug tested to calm the gut during scopes
Symptom relief Recruiting nowThis study is testing if giving an intravenous infusion of lidocaine (a common numbing medication) during an ERCP procedure can help calm unwanted gut muscle spasms. Researchers want to see if this reduces the need for extra 'rescue' spasm drugs, lowers the amount of sedation med…
Matched conditions: SEDATION
Phase: PHASE4 • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Pill vs IV sedation: which helps older minds recover faster after eye surgery?
Symptom relief Recruiting nowThis study tests whether taking a calming pill works as well as receiving sedation through an IV for older adults having cataract surgery. Researchers want to know which method is safer and helps people recover their thinking and memory faster after the procedure. Participants wi…
Matched conditions: SEDATION
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Mar 24, 2026 12:01 UTC
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Last-Resort sedation offered for agitated ICU patients
Symptom relief AVAILABLEThis program provides access to an inhaled sedative (isoflurane) for critically ill adults on breathing machines in the ICU who cannot be adequately calmed with standard IV medications. It is for patients who remain agitated, harm themselves, or develop serious side effects from …
Matched conditions: SEDATION
Sponsor: Sedana Medical • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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New sedation drug tested for safer, smoother endoscopies
Symptom relief Recruiting nowThis study is testing whether a newer sedation drug called remimazolam works as well as the commonly used drug propofol for keeping patients comfortable during routine endoscopic procedures like colonoscopies. It will enroll 100 adults to see if the new drug is a practical option…
Matched conditions: SEDATION
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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ICU sleep study: which computer gets the dose right?
Knowledge-focused Recruiting nowThis study aims to find out which of two computer models is better at keeping ICU patients on ventilators at the right level of sedation. Researchers will observe 84 patients to see which model (Eleveld or Schnider) more accurately maintains the target sedation depth and leads to…
Matched conditions: SEDATION
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC