New sedation cocktail aims to protect elderly patients during routine scopes
NCT ID NCT07707258
First seen Jul 16, 2026 · Last updated Jul 22, 2026 · Updated 3 times
Summary
This trial investigates whether combining two drugs, remimazolam and oliceridine, can provide safer sedation for elderly patients (ages 65-80) undergoing painless gastrointestinal endoscopy. The goal is to maintain stable breathing and blood pressure while reducing risks like low oxygen levels and cognitive changes after the procedure. Participants will be randomly assigned to receive either the new combination or the standard sedative sufentanil, and their vital signs will be closely monitored.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- remimazolam combined with oliceridine
- What this could lead to
- If successful, this could lead to a safer sedation option for elderly patients undergoing gastrointestinal endoscopy, with fewer breathing and blood pressure complications.
- What could go wrong
- This is a small, early-stage trial, so results may not apply to all elderly patients. The combination might still cause side effects like low oxygen or blood pressure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shanghai Baoshan District Dachang Hospital (Renji Hospital Baoshan Branch)
RECRUITINGShanghai, Shanghai Municipality, 200444, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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