SEDATION
Clinical trials for SEDATION explained in plain language.
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New sedative could speed recovery for ventilator patients
Symptom relief TerminatedThis study tests a new sedative called remimazolam for people in the ICU who need a breathing tube after oral or facial surgery. It compares remimazolam to two standard sedatives, propofol and midazolam, to see if it works just as well and helps patients wake up faster. The trial…
Matched conditions: SEDATION
Phase: PHASE4 • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Which Pre-Surgery drug calms nerves and eases pain best?
Symptom relief OngoingThis study tests two medications, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. Ninety adults will receive one of the drugs or a placebo before spinal anesthesia. Researchers will measure anxiety levels and pain sc…
Matched conditions: SEDATION
Phase: NA • Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New sedation study aims to make endoscopy easier for patients
Symptom relief OngoingThis study compares two sedative drugs, remimazolam and propofol, for people having an endoscopy (a tube with a camera used to look inside the body). The goal is to see which drug works better and is safer. About 100 adults will take part, and the study will track how many people…
Matched conditions: SEDATION
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Nasal sprays for jaw surgery: which sedative works best?
Symptom relief ENROLLING_BY_INVITATIONThis study compares two sedative drugs (midazolam and dexmedetomidine) given as nasal sprays to 32 people having surgery for a broken lower jaw. The goal is to see which drug provides better sedation and how they affect heart rate and blood pressure. Participants are healthy adul…
Matched conditions: SEDATION
Phase: EARLY_PHASE1 • Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Ketamine may offer better pain relief during biopsies than standard sedation
Symptom relief OngoingThis study tests whether ketamine, combined with midazolam, can reduce pain better than the usual fentanyl and midazolam combination for patients undergoing biopsies or drainage procedures. About 276 adults will be randomly assigned to one of the two sedation methods. Researchers…
Matched conditions: SEDATION
Phase: EARLY_PHASE1 • Sponsor: CAMC Health System • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC