Ketamine may offer better pain relief during biopsies than standard sedation

NCT ID NCT07040163

Ongoing Symptom relief Sponsor: CAMC Health System Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether ketamine, combined with midazolam, can reduce pain better than the usual fentanyl and midazolam combination for patients undergoing biopsies or drainage procedures. About 276 adults will be randomly assigned to one of the two sedation methods. Researchers will track pain scores, side effects, and patient satisfaction to see if ketamine improves the experience without raising risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ketamine
What this could lead to: If ketamine works better, it could offer a safer, more comfortable sedation option for common interventional radiology procedures.
What could go wrong: This is an early-phase trial with 276 participants, so results may not apply to everyone. Ketamine can cause side effects like hallucinations or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIOPSY DRAINAGE PROCEDURE INTERVENTIONAL RADIOLOGY SEDATION

Contacts and locations

Locations

CAMC Memorial

Charleston, West Virginia, 25304, United States

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