Which sedation drug is safer for mom and baby during C-Section?

NCT ID NCT07676955

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study compares two medications—dexmedetomidine and low-dose ketamine—given as a single dose before a planned C-section under spinal anesthesia. Both groups then receive a steady infusion of dexmedetomidine to keep them comfortable. Researchers will measure how well each drug sedates the mother, her blood pressure and heart rate, satisfaction scores, and the baby's health right after birth. The goal is to find which approach offers better comfort with fewer side effects for both mother and newborn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dexmedetomidine and ketamine

What this could lead to

If one drug proves better, it could improve comfort and safety for mothers undergoing planned C-sections.

What could go wrong

This is a small, early-phase trial (80 people) comparing two existing drugs, so results may not apply broadly or show major differences.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sultangazi Haseki Training and Research Hospital

    Istanbul, Sultangazi, 34265, Turkey (Türkiye)