SEDATION

This study aimed to see if a 50/50 mix of oxygen and nitrous oxide (sometimes called 'laughing gas') could safely reduce pain and anxiety in children aged 1 to 16 during minor procedures like getting an IV or stitches. Researchers observed 100 children to measure their pain level…

This study tested whether giving sedation as an inhaled gas (isoflurane) works as well as the standard IV drip (propofol) for keeping adult ICU patients comfortable while on breathing machines. Researchers compared how well each method maintained the right level of calmness, how …

This study tested if listening to music could help reduce the body's stress and inflammation in critically ill adults who were sedated and on a breathing machine. 110 patients in a Spanish ICU were randomly assigned to either listen to a music session or receive standard quiet ca…

This study compared three common sedation drug combinations used during minor outpatient gynecologic surgery to see which one helps patients recover their thinking abilities fastest after the procedure. Researchers randomly assigned 120 women to receive one of the sedation method…

This study tested whether playing music for children during emergency room procedures improves their comfort and cooperation when they also receive standard sedative medication. Researchers compared children who listened to music with those who did not to see if music led to bett…

This study tested whether using a special brain monitor (a 4-channel EEG) could help doctors better manage sedation during a complex digestive procedure called ERCP. The goal was to give patients the right amount of anesthesia to keep them safe and comfortable, potentially leadin…

This study looked at two common ways to help children feel less anxious before a stomach or colon exam (endoscopy). Researchers compared letting kids watch short videos to giving them a calming nasal spray. They measured how anxious the kids were, how much sedation medicine they …

This study tested if a non-opioid drug called nefopam, given through a continuous IV drip, could safely reduce the need for strong opioid painkillers in critically ill adults on breathing machines. Researchers compared the drug to standard pain care in 60 patients to see if it lo…

This study aimed to understand how two common sedation drugs affect short-term memory and thinking in adults 65 and older after a colonoscopy. Researchers observed 164 patients, comparing the effects of propofol versus dexmedetomidine. They tested cognitive function before the pr…