New inhaled sedative could replace IV drugs for ventilated ICU patients
NCT ID NCT05327296
First seen Mar 10, 2026 · Last updated May 15, 2026 · Updated 8 times
Summary
This study tested whether an inhaled anesthetic, isoflurane, given through a special device works as well as the standard IV drug propofol for keeping ICU patients calm while on a breathing machine. About 282 adults who needed sedation for over 12 hours took part. The goal was to see if isoflurane could keep patients at the right sedation level without needing extra rescue drugs.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Memorial Health Services
Long Beach, California, 90807, United States
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Memorial Hermann Health Services
Houston, Texas, 77030, United States
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Ohio State University
Columbus, Ohio, 43210, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Stanford University
Redwood City, California, 94063, United States
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The Cooper Health System
Camden, New Jersey, 08103, United States
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The New York and Presbyterian Hospital
New York, New York, 10032, United States
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Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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University of California, San Diego
San Diego, California, 92023, United States
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University of Miami
Coral Gables, Florida, 33146, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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Virginia Commonwealth University
Richmond, Virginia, 23284, United States
Conditions
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