Can lidocaine ease ERCP spasms and cut drug use?

NCT ID NCT07333859

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving lidocaine through an IV can reduce muscle spasms in the duodenum during ERCP, a procedure to examine bile ducts. 120 adults were randomly assigned to receive lidocaine or a placebo. The goal was to see if lidocaine lowers the need for extra spasm-relief drugs and reduces the amount of sedation needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine

What this could lead to

If effective, lidocaine could become a standard option to reduce spasms and sedation needs during ERCP procedures.

What could go wrong

This is a small, single-center Phase 4 trial. Results may not apply to all patients, and lidocaine carries risks like allergic reactions or heart issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SEDATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, 06610, Turkey (Türkiye)