Pill or IV? small study tests safer sedation for Seniors' eye surgery
NCT ID NCT07154147
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether giving a sedative pill (alprazolam) before cataract surgery works as well as IV sedation (midazolam) in adults 65 and older. Twenty participants were randomly assigned to one of the two approaches, and researchers measured how well their thinking and memory recovered after surgery. The goal was not to declare a winner, but to see if a larger, more definitive study is possible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Alprazolam (Xanax) and midazolam (Versed)
What this could lead to
If successful, this pilot could pave the way for a larger study that helps determine the safest sedation method for older adults during cataract surgery.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply broadly. It is designed to test feasibility, not to prove which sedation method is better.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CATARACT are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
UCSF Wayne and Gladys Valley Center for Vision, Mission Bay
San Francisco, California, 94117, United States