Pill or IV? small study tests safer sedation for Seniors' eye surgery
NCT ID NCT07154147
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether giving a sedative pill (alprazolam) before cataract surgery works as well as IV sedation (midazolam) in adults 65 and older. Twenty participants were randomly assigned to one of the two approaches, and researchers measured how well their thinking and memory recovered after surgery. The goal was not to declare a winner, but to see if a larger, more definitive study is possible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Alprazolam (Xanax) and midazolam (Versed)
- What this could lead to
- If successful, this pilot could pave the way for a larger study that helps determine the safest sedation method for older adults during cataract surgery.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply broadly. It is designed to test feasibility, not to prove which sedation method is better.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UCSF Wayne and Gladys Valley Center for Vision, Mission Bay
San Francisco, California, 94117, United States
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