OLDER ADULTS

This trial tests whether shining a special near-infrared light on the forehead — a technique called transcranial photobiomodulation — can reduce the risk of delayed neurocognitive recovery (a form of brain fog) in older adults after surgery. The study includes people aged 65 and …

This trial tests a 16-week group program called Hopeful and Healthy Living (HHL) for adults over 50 with serious mental illness. The program combines social skills training, cognitive strategies, exercise, and healthy lifestyle education. Participants are randomly assigned to eit…

This study tests whether a daily natural supplement combined with a twice-weekly exercise program can improve immune function and reduce inflammation in adults aged 65 and older. Over six months, 60 participants will take either the supplement or a placebo, all while following th…

This study tests whether a supervised exercise program combined with oral nutritional supplements can prevent disability in hospitalized adults aged 75 and older who are malnourished or at risk. Around 102 participants will be randomly assigned to either the exercise-plus-nutriti…

This study tests a special care program designed for older adults (65+) who live alone and have limb injuries. The program, led by a nurse practitioner, includes six educational units to support recovery. Researchers will measure whether it helps reduce pain, depression, and lone…

This study tests a mobile app called ICUconnect that helps older ICU patients and their families report their needs to doctors. The goal is to improve care and reduce emotional distress. About 350 patient-family pairs will take part across four hospitals.

This study compares two 8-week programs for Black adults aged 50 and older who have chronic pain and early signs of memory decline. One program combines mindfulness-based cognitive therapy with walking, using a wrist monitor to track activity. The other focuses on staying active …

This pilot study explores whether a music-based dance program can improve thinking skills and physical function in adults aged 55 and older with mild cognitive impairment. The dance routines combine music, partner guidance, and spatial coordination to challenge memory and attenti…

This study tests a 16-week group exercise program called the Ideomotor Program in 158 healthy adults aged 50 and older. The program combines physical and mental exercises to see if it improves thinking, movement, and overall well-being. Participants will be compared to a group do…

This study tests whether health coaching can help older adults with limited mobility become more physically active. About 290 participants will either receive coaching or general health education. The goal is to see if coaching improves their ability to move and overall activity …

This study tests whether older adults (ages 65–80) can improve their leg muscle power, strength, and balance by doing simple body-weight exercises at home three times a week for eight weeks. Forty participants will be split into an exercise group and a health-education-only group…

This study tests whether a mild electrical pulse to the ear (tVNS) during finger training can help older adults learn motor skills faster. 32 healthy adults aged 65-84 will be randomly assigned to receive real or fake stimulation while practicing finger control. Researchers will …

This study looks at whether older adults with mild memory issues are more likely to become confused after planned hip replacement surgery. Researchers will test memory before surgery and watch for confusion in the first three days after. The goal is to see if a quick memory test …

This study tests whether an AI-driven fitness app and wearable can increase physical activity in adults 65 and older who live alone and have mild cognitive decline. Over six months, 64 participants will use the app and a Fitbit tracker to see if personalized exercise plans and so…

This study tests whether motivational interviewing (a supportive conversation style) can help older adults who recently visited the ER and their family caregivers complete advance care plans. 300 pairs (older adult + caregiver) will either receive three counselling sessions or a …

This study looks at ways to reduce the overuse of mammograms in women aged 75 and older, where screening may not be helpful. Researchers will test a strategy that helps doctors and patients make more informed decisions about mammograms. About 500 women and their doctors will take…

This study looks at how the immune system of adults over 75 responds to the annual flu shot. Researchers want to know if a common virus called CMV affects how well the vaccine works. Participants will receive the flu shot for free and provide blood samples over several weeks. The…

This study looks at how short-term pain affects the ability of older adults to learn and remember a new way of walking. Researchers will apply a cream with capsaicin (the stuff that makes chili peppers hot) and a heat pack to one leg to create temporary pain. Participants will wa…

This study tests whether 20 sessions of balance-challenge training on a stationary bike can improve safe cycling skills in adults aged 65 and older. Participants will be randomly assigned to the training or a control group, and their cycling ability will be measured on a test cou…

This study tests whether a mobile health program using WhatsApp video calls can help homebound older adults manage their own care better. 130 participants aged 60+ will receive six coaching sessions over three months from a nurse. The goal is to see if this person-centered approa…