OLDER ADULTS
Clinical trials for OLDER ADULTS explained in plain language.
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Exercise and diet combo may help obese seniors get fit faster
Disease control CompletedThis study looked at 180 obese, sedentary older adults to see if losing fat through a controlled diet while exercising improves their heart and lung fitness more than exercise alone. Participants followed a standard exercise program and some also reduced calories to lose weight. …
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Walking in the hospital could keep seniors out of nursing homes
Symptom relief CompletedThis study tested a program called MOVIN that encourages older hospital patients (65+) to walk more during their stay. Researchers wanted to see if this simple change could prevent disability and help patients recover better after leaving the hospital. Over 700 patients and many …
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 17, 2026 05:35 UTC
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Beef vs. veggies: which diet fights muscle fatigue in seniors?
Symptom relief CompletedThis study looked at whether eating beef can reduce muscle fatigue in older adults compared to a plant-based diet. Twenty-four people aged 60-85 ate either a beef or vegetarian diet for 8 weeks, then switched after a break. Researchers measured muscle strength and blood markers t…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated May 17, 2026 05:33 UTC
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Virtual forest bathing: VR nature lifts spirits in seniors
Symptom relief CompletedThis study explored whether virtual reality (VR) nature scenes can improve mood and reduce anxiety in older adults who have trouble getting outside. Thirty adults aged 60–90 used VR to experience natural environments. Researchers measured changes in mood, anxiety, and depressive …
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Universitat Internacional de Catalunya • Aim: Symptom relief
Last updated May 17, 2026 05:32 UTC
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12-Week fitness boost shows promise for seniors with mobility issues
Symptom relief CompletedThis small pilot study tested a 12-week high-intensity functional training program for adults aged 60 and older who have a long-term mobility disability but can still walk. The goal was to see if the program is feasible and can improve walking speed, endurance, balance, and leg s…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Kansas • Aim: Symptom relief
Last updated May 17, 2026 05:31 UTC
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New program eases depression and anxiety in seniors facing joint replacement
Symptom relief CompletedThis study tested a program that combines counseling and medication adjustments to reduce depression and anxiety in adults aged 60 and older who were scheduled for hip or knee replacement surgery. 116 participants were split into two groups: one received the program plus usual ca…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 17, 2026 05:29 UTC
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Brain training boosts thinking in older HIV patients
Symptom relief CompletedThis study tested whether 20 hours of executive function training could improve thinking skills and reduce mental ups and downs in adults over 40 with HIV-related cognitive problems. 119 participants were split into a training group and a no-contact control group. The goal was to…
Matched conditions: OLDER ADULTS
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 17, 2026 05:29 UTC
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Art program lifts depression and age stigma in seniors, study finds
Symptom relief CompletedThis study tested whether a cultural arts program could reduce depressive symptoms and age-related self-stigma in older adults. 63 participants aged 60+ who were at risk for depression took part. The program involved creative arts activities, and results were compared to usual se…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated May 17, 2026 05:28 UTC
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New approach eases depression and anxiety in older heart surgery patients
Symptom relief CompletedThis study tested a program that combines counseling (behavioral activation) with medication adjustments to help older adults feel less depressed and anxious before and after heart surgery. 105 people aged 60 and older took part. The goal was to see if this program works better t…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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New approach eases anxiety and depression in older cancer surgery patients
Symptom relief CompletedThis study looked at whether a combination of behavioral counseling and medication adjustments could reduce anxiety and depression in adults aged 60 and older who were about to have surgery for cancer. About 105 participants were randomly assigned to receive this support or usual…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Online workouts boost strength in seniors with prediabetes
Symptom relief CompletedThis study looked at whether a live, online strength training program called Vivo is practical and helpful for older adults with prediabetes. Twenty-eight sedentary adults aged 60 and older took part in 12 weeks of supervised workouts from home. The results showed good attendance…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Eric Levian • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Exercise program boosts brain and body in seniors
Symptom relief CompletedThis study tested whether a 12-week group exercise program (twice a week, 45-60 minutes per session) could help older adults become less frail, improve memory and thinking, and sleep better. A total of 110 adults aged 65 and older took part. The program included a mix of exercise…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Neslihan Lok • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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Friendly calls combat loneliness and suicide risk in seniors
Symptom relief CompletedThis study tested whether regular supportive phone calls could improve mental health in older adults who receive meal services and may feel lonely or isolated. Over 670 participants aged 55+ either received 8 weeks of 'warm calls' from trained helpers or were in a comparison grou…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Florida • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Tiny study asks: does MBT work for Over-60s?
Knowledge-focused CompletedThis study looked at whether Mentalization-Based Therapy (MBT) helps people aged 60 and older who struggle in relationships. Three participants received MBT, and researchers used interviews and questionnaires to see if it improved their mental health and ability to understand oth…
Matched conditions: OLDER ADULTS
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated May 17, 2026 05:36 UTC
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Pill vs needle: could a simple oral sedative be safer for older adults during cataract surgery?
Knowledge-focused CompletedThis study tested whether giving older adults a pill (oral sedation) instead of medicine through an IV (intravenous sedation) before cataract surgery is a good option. Twenty people aged 65 and older took part. The goal was to see if it's possible to run a larger study comparing …
Matched conditions: OLDER ADULTS
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 17, 2026 05:29 UTC
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Study reveals surprising links between exercise and happiness in seniors
Knowledge-focused CompletedThis study looked at how physical activity, life satisfaction, and taking medicine as prescribed are related in older adults with chronic conditions. Researchers surveyed 82 people aged 65 and older who had at least one chronic disease like high blood pressure or diabetes. They u…
Matched conditions: OLDER ADULTS
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Walk your way to better health: new study tests simple program for seniors
Knowledge-focused CompletedThis study looked at whether a structured program based on the SOC model could help older adults (65+) walk more and feel better. 350 participants in Jiazhou, China took part. The program focused on teaching strategies to plan and adapt walking routines. Researchers measured walk…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: Ling Yang • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Blood pressure pills may change brain blood flow in seniors
Knowledge-focused CompletedThis study looked at how blood pressure medications affect brain blood flow and thinking skills in older adults with high blood pressure. Researchers gave 27 participants either a drug or a placebo for 1-2 weeks and measured brain blood flow, nerve activity, and cognitive functio…
Matched conditions: OLDER ADULTS
Phase: EARLY_PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Can lifestyle changes and supplements boost aging brains?
Knowledge-focused CompletedThis pilot study tested whether combining lifestyle changes, risk factor management, medications, and supplements could improve movement, thinking, and immune health in adults aged 50-70. The main goal was to see if the approach was feasible, not to prove it works. Only 23 people…
Matched conditions: OLDER ADULTS
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Game on for oral health: app boosts cancer knowledge in seniors
Knowledge-focused CompletedThis study tested whether a mobile app with educational videos and serious games improves oral cancer knowledge and oral hygiene in adults aged 60 and older. 62 participants used either a version with videos and games or videos only for 4 weeks. The goal was to see if the interac…
Matched conditions: OLDER ADULTS
Phase: NA • Sponsor: University of Chile • Aim: Knowledge-focused
Last updated May 04, 2026 16:22 UTC