New combo therapy aims to lift mood after heart surgery in seniors
NCT ID NCT05575128
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a program combining behavioral activation (helping people do meaningful activities) and medication optimization (adjusting meds) can reduce depression and anxiety in adults 60 and older undergoing heart surgery. 105 participants were split into two groups: one received the program, the other usual care. The goal was to see if symptoms improved 3 months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
behavioral activation and medication optimization
What this could lead to
If it works, this could offer a simple, drug-free way to improve mental health recovery after heart surgery in older adults.
What could go wrong
This is a small, completed study (105 participants) without a later phase, so results may not apply broadly. The intervention combines two approaches, making it hard to know which part helped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Washington University in St. Louis
St Louis, Missouri, 63110, United States