Flu shot study targets immune response in the oldest old

NCT ID NCT02200276

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study looks at how the immune system of adults over 75 responds to the annual flu shot. Researchers want to know if a common virus called CMV affects how well the vaccine works. Participants will receive the flu shot for free and provide blood samples over several weeks. The goal is to better understand vaccine effectiveness in this age group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University; JHAAC 5501 Hopkins Bayview Circle, 1B84

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Influenza vaccine (flu shot)

What this could lead to

If successful, this study could help improve flu vaccination strategies for older adults, especially those over 75.

What could go wrong

This is an observational study, not a treatment trial. It aims to gather knowledge, not test a new therapy. Results may not lead to immediate changes in practice.

Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.