Flu shot study targets immune response in the oldest old

NCT ID NCT02200276

Recruiting now Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the immune system of adults over 75 responds to the annual flu shot. Researchers want to know if a common virus called CMV affects how well the vaccine works. Participants will receive the flu shot for free and provide blood samples over several weeks. The goal is to better understand vaccine effectiveness in this age group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Influenza vaccine (flu shot)
What this could lead to: If successful, this study could help improve flu vaccination strategies for older adults, especially those over 75.
What could go wrong: This is an observational study, not a treatment trial. It aims to gather knowledge, not test a new therapy. Results may not lead to immediate changes in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNIZATION INFLUENZA OLDER ADULTS OVER AGE 75

Contacts and locations

Locations

Johns Hopkins University; JHAAC 5501 Hopkins Bayview Circle, 1B84
RECRUITING

Baltimore, Maryland, 21224, United States

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