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Mindfulness and walking may ease pain and protect memory in older black adults

NCT ID NCT06246929

Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study compares two 8-week programs for Black adults aged 50 and older who have chronic pain and early signs of memory decline. One program combines mindfulness-based cognitive therapy with walking, using a wrist monitor to track activity. The other focuses on staying active through everyday living. Researchers will measure changes in physical function, thinking skills, and emotional well-being, and check if improvements last for six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mindfulness-Based Cognitive Therapy with Walking (MBCT+w) and Active Living Every Day (ALED)
What this could lead to
If successful, this could point toward effective, non-drug programs that help older Black adults maintain physical function and slow cognitive decline while managing chronic pain.
What could go wrong
This is a comparative effectiveness trial, not a test of a new drug. Results may show only modest benefits, and individual responses can vary. The programs require commitment to weekly sessions and home practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Black adults, male and females, age 50 or older * Have nonmalignant musculoskeletal chronic pain for more than three months * Reports early cognitive decline (subjective and objective) * Telephone Interview for Cognitive Status-41 score greater than or equal to 31 * Functional Activities Questionnaire score less than 9 * English fluency/literacy * Free of concurrent psychotropic or pain medication for at least 2 weeks prior to initiation of treatment, OR stable on current psychotropic or pain medication for a minimum of 6 weeks and willing to maintain stable dose * Cleared by medical doctor for study participation and no self-reported concerns about physical functioning on the revised Physical Activity Readiness Questionnaire (PAR-Q; score 0) Exclusion Criteria: * Diagnosed with dementia or neurodegenerative disease * Regular use of nonpharmacological pain management * Diagnosed with serious mental illness or substance abuse * Current suicidal ideation on self-report * Engagement of regular exercise for more than 30 minutes daily * Unable to walk

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Cognition Disorders Cognitive Dysfunction Motor Activity Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Mild cognitive impairment Older adults Physical activity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

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