Colonoscopy sedation study: which drug is safer for Seniors' brains?
NCT ID NCT07384169
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at 164 adults aged 65 and older who had a colonoscopy with sedation. Researchers compared two common sedatives—propofol and dexmedetomidine—to see how they affected thinking and memory. They also checked whether frailty played a role. Participants took a simple thinking test before the procedure and again 2 and 24 hours after. The goal was to find out which sedation method might be safer for older patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
propofol and dexmedetomidine
What this could lead to
If it works, this could help doctors choose the safest sedation method for older adults undergoing colonoscopy to protect their thinking skills.
What could go wrong
This is a small, completed observational study, not a large trial. Results may not apply to all older adults or other procedures.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ankara Bilkent City Hospital
Ankara, Çankaya, 06800, Turkey (Türkiye)