Colonoscopy sedation study: which drug is safer for Seniors' brains?

NCT ID NCT07384169

Completed Knowledge-focused Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at 164 adults aged 65 and older who had a colonoscopy with sedation. Researchers compared two common sedatives—propofol and dexmedetomidine—to see how they affected thinking and memory. They also checked whether frailty played a role. Participants took a simple thinking test before the procedure and again 2 and 24 hours after. The goal was to find out which sedation method might be safer for older patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: propofol and dexmedetomidine
What this could lead to: If it works, this could help doctors choose the safest sedation method for older adults undergoing colonoscopy to protect their thinking skills.
What could go wrong: This is a small, completed observational study, not a large trial. Results may not apply to all older adults or other procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Frailty

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITION COLONOSCOPY FRAILTY GERIATRIC ANESTHESIA SEDATION

Contacts and locations

Locations

Ankara Bilkent City Hospital

Ankara, Çankaya, 06800, Turkey (Türkiye)

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