COGNITION

This study is testing whether a special exercise program can help people with early memory loss due to Alzheimer's disease. Researchers want to see if exercises that combine physical and mental tasks can improve walking, balance, and thinking skills better than regular exercise o…

This study is observing how esketamine nasal spray works for people with severe, treatment-resistant depression in real-world clinics. It aims to see who benefits most from the treatment and how it affects their daily life, work, and social functioning. Researchers will also look…

This small pilot study is testing whether taking whey protein supplements can help older adults who are starting to show signs of frailty. Researchers want to see if the protein improves brain antioxidant levels, measured by MRI scans, and also helps with strength, balance, and t…

This study is testing whether eating freeze-dried wild blueberry powder every day for six months can help control high blood pressure, improve gut bacteria, and enhance memory and thinking skills. It will involve 40 Black and White adults aged 45-65 who have elevated blood pressu…

This study is testing whether a 6-month, at-home brain stimulation treatment can improve memory and walking ability in older adults who show early signs of dementia risk. Participants aged 65-90 will use a device that delivers mild electrical currents to the brain through the sca…

This study is testing whether a mobile app for parents can help their 3-4 year old children follow healthy daily movement guidelines. Researchers will compare 80 families using the app to a group that gets it later. The app provides weekly tips and goals to encourage more physica…

This global study is testing whether painting roofs with special reflective coatings can keep homes cooler and prevent heat-related health problems. Researchers are working with 3,200 people in five hot climate regions where housing conditions make residents especially vulnerable…

This study is testing whether taking an amino acid supplement called L-serine, either by itself or combined with strength training, can help improve mental sharpness, brain function, and physical fitness in healthy older adults. Researchers will enroll 126 men and women aged 65 t…

This study is testing whether a daily nutrient shake helps older adults recover their physical strength and thinking skills after major surgery. Half of the 100 participants will receive the shake for one month after leaving the hospital, while the other half will receive standar…

This study is testing whether a phone app and monthly coaching calls can help firefighters get better sleep. Fifty firefighters will try the app for three months, tracking sleep and learning healthy habits, while others receive basic sleep information. The main goal is to see if …

This study is testing whether a daily liquid dietary supplement can improve memory, focus, and mood in healthy adults aged 55 and older. Participants will take the supplement or a control drink for 45 days and complete memory and mood tests at the start and end. The goal is to se…

This study is testing if using a virtual reality (VR) headset to do fun, game-like exercises is better than standard physical therapy for people with a 'frozen shoulder.' Researchers want to see if the VR exercises can help reduce pain, improve shoulder movement, and also help wi…

This study is testing a special exercise program called 'sport stacking' (quickly stacking and unstacking cups) for people with mild dementia and the family members who care for them. The goal is to see if doing these activities together can help improve the person's thinking ski…

This study is testing whether a single dose of an American ginseng supplement can improve attention and mental performance in healthy young adults. Researchers will give 200 participants either the supplement or a placebo and measure their focus, memory, and reaction time over 6 …

This study is testing whether special 'dynamic' lighting in hospital rooms can help improve sleep and daily rhythms for elderly patients. It will involve 300 patients over age 65 who are hospitalized. Researchers will compare patients in rooms with the special lighting to those i…

This study is testing whether a brain training program that combines strategy coaching with attention exercises can help veterans with mild brain injury and PTSD improve their thinking skills and ability to handle daily tasks. Researchers are comparing whether delivering this tra…

This study aims to understand how decision-making works in conditions like schizophrenia. Researchers are giving a single dose of a medication called modafinil to healthy volunteers and measuring changes in their brain activity and performance on computer 'brain games.' The goal …

This study aims to understand the long-term effects of using interactive devices like tablets and smartphones on young children's development and health. Researchers will follow nearly 900 children in England, aged 3 to 5, tracking their device use with a special app and measurin…

This study is investigating whether eating a daily mix of nuts for six months can improve mental health, reduce stress, and enhance thinking skills in young adults. It will involve 135 university students aged 18-25 who will be randomly assigned to either eat nuts or not. Researc…

This study is testing whether a non-invasive light therapy helmet can improve how the brain regulates blood flow during thinking tasks and if this helps memory and thinking skills in older adults. Researchers will compare the real light treatment to a fake one in 30 participants …

This study aims to build a detailed research database to help scientists develop better ways to detect, prevent, and treat Alzheimer's disease. It will enroll 1,000 adults aged 60 and older, including those with and without memory problems. Participants will be followed annually …

This study aims to understand if low levels of magnesium in the blood are connected to memory and thinking problems people often experience after a stroke. Researchers will follow 80 stroke patients, measuring their magnesium levels and testing their thinking skills at several po…

This study is testing whether giving young children a daily prebiotic fiber supplement for 8 weeks can improve their thinking skills, behavior, and the balance of bacteria in their gut. It will involve about 106 healthy children aged 3-5 who don't eat much fiber. Researchers will…

This study aims to understand how obstructive sleep apnea affects children's thinking skills and ability to understand others' feelings. Researchers will follow 150 children aged 3-12 with sleep apnea for 12 months, comparing those who receive surgery versus medication. The study…

This study aims to understand how the brain helps people plan multiple steps ahead. Healthy adult volunteers will play a strategy game similar to Connect Four while researchers measure their brain activity using scanners. The goal is to learn how people mentally simulate future m…