COGNITION

This study tests if special reflective roof coatings can lower indoor temperatures and improve health in hot, poor communities. About 3,200 people in Burkina Faso, Mexico, India, Niue, and Fiji will take part. Researchers will measure heart rate, blood sugar, mood, and other heal…

This study looks at whether eating peanuts every day can improve blood sugar, blood pressure, thinking skills, and gut health in adults with prediabetes. Researchers will enroll 72 racially diverse men and women aged 20-59. Participants will eat peanuts or avoid them for set peri…

This study tests whether a freeze-dried wild blueberry powder can improve heart health, brain function, and gut bacteria in 30 women aged 20-65 with prediabetes and overweight. Participants will take the powder and have their blood sugar, blood pressure, and thinking skills measu…

This study looks at whether eating wild blueberries can improve heart health, thinking skills, and gut bacteria in Black and White adults aged 45-65 with high blood pressure. Researchers will measure blood pressure, artery stiffness, and memory over time. The goal is to see if a …

This study tests whether taking ETAS® supplements daily for 12 weeks can improve memory, mood, and sleep in healthy adults aged 60-80 who have mild memory complaints. Researchers will use brain scans and thinking tests to measure any changes. The goal is to see if this natural su…

This study tests whether a special brain training program, delivered either in-person or via telehealth, can improve attention and thinking skills in veterans with mild traumatic brain injury and PTSD. About 63 veterans will participate. The goal is to see if the remote option wo…

This study tests whether a safe, low-level electrical stimulation device used at home for 6 months can improve thinking and walking in older adults (ages 65-90) who have memory concerns and walk slowly—signs of increased dementia risk. Participants will use a headset daily and be…

This study tests whether a sport stacking (cup stacking) program can improve health and quality of life for people with mild dementia and their family caregivers. About 144 pairs (person with dementia and their caregiver) will take part in online group sessions and home practice …

This study tests whether giving prebiotics (a type of fiber) every day to 3-5 year olds who don't eat enough fiber can improve their sleep, mood, thinking, and gut health. About 106 children will take either a prebiotic or a placebo for several weeks. Parents will report on their…

This study tests whether a daily dietary supplement can improve memory, thinking, and emotional well-being in healthy adults aged 55 and older. Sixteen participants will take the supplement for 45 days and complete memory and mood tests at the start and end. The goal is to see if…

This study looks at whether adding breathing exercises to balance training can improve thinking skills in people aged 65 and older. Participants will attend two 45-minute sessions per week for 8 weeks, combining balance exercises with one of two breathing techniques. Researchers …

This study looks at whether eating nuts can improve mental health in young adults. Researchers will measure changes in depression, anxiety, stress, memory, and thinking skills in 135 university students aged 18 to 25. Participants will eat nuts regularly, and the team will track …

This study tests whether a special type of lighting that changes throughout the day can improve sleep, body clock function, and overall well-being in frail adults aged 65 and older who are staying in the hospital. Researchers will measure changes in melatonin levels and sleep pat…

This study tests whether immersive virtual reality exercise can reduce pain, improve shoulder function, sleep, and thinking in people with mild to moderate frozen shoulder (grade 1-2). About 36 adults aged 18-64 who are new to physical therapy will use VR headsets for gamified ex…

This study looks at whether a single dose of a supplement containing American Ginseng can improve attention and brain function in healthy young adults aged 18 to 40. Participants will take the supplement and then complete memory and thinking tests over 6 hours, with blood samples…

This small study is testing whether taking whey protein can increase antioxidant levels in the brain and improve physical function, body composition, and thinking skills in older adults who are showing early signs of frailty. Twenty pre-frail volunteers aged 65 to 85 will take wh…

This study is testing if a special exercise program can help people with early memory loss from Alzheimer's disease. Researchers want to see if exercises that combine physical and mental tasks can improve walking, balance, and thinking skills. They will compare this program to re…

This study looks at how chronic marijuana use changes brain inflammation and thinking skills in people with HIV. Researchers will use brain scans and blood tests to measure brain health in 220 adults, comparing those who use marijuana regularly with those who do not. The goal is …

This study tests whether a home-based mobile app can help parents of 3-4 year olds improve their child's daily physical activity, sleep, and screen time. About 80 children who currently meet few or no movement guidelines will wear activity trackers and have motor skills tested. P…

This study looks at how healthy adults think ahead when making decisions. Volunteers will play a strategy game similar to Connect Four while researchers record their brain activity and eye movements. The goal is to understand the mental steps people take when planning multiple mo…

This study is testing whether a special nutritional shake given after surgery can help older adults (70+) recover their physical and mental abilities faster. Half of the 100 participants will receive the shake daily for 30 days, while the other half will follow standard recovery …

This study looks at how the antipsychotic medication haloperidol affects insulin action in the brain. Insulin helps control blood sugar and brain function, but haloperidol can cause weight gain and diabetes. Researchers will give healthy volunteers haloperidol and use brain scans…

This study looks at how obstructive sleep apnea (OSA) affects thinking skills and empathy in children aged 3 to 12. Researchers will compare surgery versus medication for mild OSA and track changes over a year. They will also search for brain wave patterns that could show early d…

This study is building a large group of 1,000 older adults (age 60+) to help researchers better understand Alzheimer's disease. Participants include people with normal memory, mild memory problems, or Alzheimer's. They will have yearly check-ups, brain scans, and blood or spinal …

This study looks at how a single dose of modafinil changes decision-making and brain activity in healthy adults. Researchers hope to learn more about psychosis spectrum disorders like schizophrenia. Participants will take one dose of modafinil, play computer brain games, and wear…

This study looks at whether a whey protein-enriched milk fat globule membrane supplement can improve markers of heart and brain health after a high-fat meal. Sixteen postmenopausal women who are overweight and at moderate risk for heart disease will take the supplement or a place…

This study looks at whether taking L-serine (an amino acid) with or without strength training can improve memory, thinking, and physical fitness in healthy adults aged 65 to 85. Participants are split into three groups: placebo, L-serine alone, or L-serine plus strength training.…

This study is testing whether a smartphone app can help firefighters improve their sleep, thinking, and overall health. About 50 firefighters will use the app and report how well it works. The goal is to see if the program is easy to use and helpful for this group.

This study is following 874 children aged 3 to 5 in England for one year to understand how using tablets and smartphones affects their thinking skills, health, and school readiness. Parents will install an app that tracks what children do on their devices. The goal is to provide …

This study looks at whether low magnesium levels in the blood are linked to memory, thinking, and other cognitive problems after a stroke. Researchers will measure magnesium and cognitive function in 80 stroke patients over time. The goal is to understand if magnesium deficiency …

This study watches 100 adults with treatment-resistant depression who are taking esketamine nasal spray as part of their normal care. Researchers want to see how well it works, who improves most, and how it affects daily life, work, and mood. They will also look at genes and brai…

This study tests whether shining a special near-infrared light on the head (transcranial photobiomodulation) can improve blood flow and thinking in older adults. Researchers will compare active treatment to a sham (fake) treatment over 4 weeks in 30 healthy volunteers aged 21-85.…