COGNITION

This study looks at whether eating peanuts every day can improve blood sugar, blood pressure, thinking skills, and gut health in adults with prediabetes. Researchers will enroll 72 racially diverse adults aged 20-59 who have prediabetes but no peanut allergies. Participants will …

This study tests if special reflective roof coatings can lower indoor temperatures and improve health in hot regions. About 3,200 people living in poor housing in Burkina Faso, Mexico, India, Niue, and Fiji will take part. Researchers will measure heart rate, blood sugar, mood, a…

This study looks at whether a daily dose of freeze-dried wild blueberry powder can improve blood sugar, blood pressure, and thinking skills in women aged 20-65 who have prediabetes and are overweight. Researchers will also check if it changes gut bacteria. The goal is to see if t…

This study looks at whether eating wild blueberries can improve heart health, thinking skills, and gut bacteria in adults aged 45-65 with high blood pressure. Researchers will measure blood pressure, artery stiffness, and memory over time. The goal is to see if a simple diet chan…

This study tests a new exercise program for people with mild cognitive impairment (early memory loss) due to Alzheimer's. The program focuses on doing two tasks at once, like walking while counting. Researchers want to see if it improves walking, balance, and thinking. About 45 a…

This study tests whether using a safe, low-current brain stimulation device at home for 6 months can improve thinking and walking in older adults (ages 65-90) who have memory concerns and walk slowly, putting them at higher risk for dementia. Participants will use a headset for 2…

This study tests whether taking ETAS® supplements daily for 12 weeks can improve memory, mood, and sleep in healthy adults aged 60-80 who have mild memory complaints. Researchers will use brain scans and thinking tests to measure any changes. The goal is to see if this supplement…

This study explores whether immersive virtual reality-based exercise therapy can reduce pain, improve shoulder function, sleep, and thinking skills in people with mild-to-moderate frozen shoulder (Grade 1-2 adhesive capsulitis). Researchers will enroll 36 adults aged 18-64 who ar…

This study looks at whether a single dose of a supplement made from American Ginseng can improve attention and brain function in healthy young adults aged 18 to 40. Participants will take the supplement and then complete memory and thinking tests over 6 hours. Blood samples will …

This small study is testing whether taking whey protein can increase antioxidant levels in the brain and improve physical function, thinking skills, and body composition in older adults who are pre-frail. Twenty participants aged 65 to 85 will take whey protein and undergo MRI sc…

This study looks at whether eating nuts can help reduce symptoms of depression, anxiety, and stress in young adults aged 18 to 25. Researchers will also measure memory, thinking skills, and a brain-related protein called BDNF. A total of 135 university students will be randomly a…

This study tests whether giving prebiotics (a type of fiber) daily for several weeks can improve mood, sleep, thinking, and gut health in 106 children aged 3-5 who don't get enough fiber. Parents will report on their child's behavior and emotions. The goal is to see if a simple d…

This study looks at whether a whey protein-enriched milk fat globule membrane supplement can improve heart and brain health after a high-fat meal. Sixteen postmenopausal women with overweight and moderate heart disease risk will drink either the supplement or a placebo. Researche…

This study tests whether a daily dietary supplement can improve memory, thinking, and emotional well-being in healthy adults aged 55 and older. Sixteen participants will take the supplement for 45 days and complete memory and mood tests at the start and end. The goal is to see if…

This study tests whether a special brain training program, delivered either in-person or via telehealth, can improve attention and thinking skills in veterans with mild traumatic brain injury and PTSD. About 63 veterans will participate. The goal is to see if the remote option wo…

This study tests whether a sport stacking (cup stacking) program can improve health and quality of life for people with mild dementia and their family caregivers. About 144 pairs (person with dementia and their caregiver) will take part in online group sessions and home practice …

This study tests whether a special type of dynamic lighting can improve sleep, daily rhythms, and overall well-being in frail older adults (65+) who are in the hospital. Researchers will measure changes in melatonin levels and sleep patterns. The goal is to find a simple, non-dru…

This study looks at whether adding breathing exercises to balance training can improve thinking skills in people aged 65 and older. Participants will attend two 45-minute sessions per week for 8 weeks, combining balance exercises with one of two breathing techniques. Researchers …

This study looks at whether a special nutrition shake can help frail older adults recover their strength and thinking abilities after major surgery. Half of the 100 participants will receive the shake daily for 30 days after surgery, while the other half will get standard recover…

This study looks at whether low magnesium in the blood is linked to memory and thinking problems after a stroke. Researchers will measure magnesium levels and cognitive skills in 80 stroke patients over time. The goal is to understand if magnesium deficiency plays a role in post-…

This study tests a painless light therapy called transcranial photobiomodulation (tPBM) to see if it can improve blood flow and thinking in older adults. Thirty healthy people aged 21-85 will receive either real or fake light sessions over 4 weeks. Researchers will measure brain …

This study follows 100 adults with treatment-resistant depression who are prescribed esketamine nasal spray as part of their regular care. Researchers will track how well the drug works, who responds best, and how it affects daily life, work, and social functioning. The goal is t…

This study is building a large group of 1,000 older adults (age 60+) in Tennessee to help researchers better understand Alzheimer's disease. Participants include people with normal memory, mild memory problems, or Alzheimer's. They will have yearly check-ups, brain scans, and blo…

This study will follow 874 children aged 3 to 5 for one year to understand how using tablets and smartphones affects their thinking, health, and school readiness. Parents will use an app to track their child's screen time, and researchers will measure skills like memory, attentio…

This study looks at how chronic marijuana use impacts brain inflammation and thinking skills in people with HIV. Researchers will use brain scans and cognitive tests to compare marijuana users and non-users. The goal is to understand whether marijuana helps or harms brain health …

This study is testing whether a smartphone app can help firefighters improve their sleep, thinking, and overall well-being. About 50 firefighters will use the app and report on their sleep habits. The goal is to see if the program is easy to use and helpful for this group.

This study looks at how healthy adults think ahead when making decisions. Volunteers will play a game similar to Connect Four while researchers record their brain activity and eye movements. The goal is to understand the brain processes behind multi-step planning. This is an obse…

This study looks at whether taking the amino acid L-serine, alone or with strength training, can improve memory, thinking, and physical fitness in healthy older adults. Researchers will track 126 people aged 65-85 over 48 weeks using cognitive tests, blood work, and brain scans. …

This study looks at how haloperidol, an antipsychotic medication, may interfere with insulin's normal action in the brain. Insulin helps control blood sugar and supports brain function, but long-term use of haloperidol can lead to weight gain and diabetes. Researchers will give h…

This study looks at how obstructive sleep apnea (OSA) affects children's ability to think, control impulses, and understand others' feelings. Researchers will follow 150 children aged 3-12 for one year, comparing surgery versus medication for mild OSA. They will also check if bra…

This study tests whether a home-based mobile app can help parents of 3-4 year olds improve their child's daily physical activity, sleep, and screen time. About 80 children who currently meet few or no movement guidelines will wear activity trackers and have motor skills tested. P…

This study looks at how a single dose of modafinil changes decision-making and brain activity in healthy adults. Researchers hope to learn more about psychosis spectrum disorders like schizophrenia. Participants will take one dose of modafinil, play computer brain games, and wear…