COGNITION

This study tests if special reflective roof coatings can lower indoor temperatures and improve health in Fiji. About 800 households will receive either a cool roof or usual care. Researchers will measure heart rate, blood sugar, depression, and other heat-related symptoms to see …

This study will test whether applying a special heat-reflecting coating to roofs can improve the health and well-being of 800 households in Colima, Mexico. The coating is designed to keep homes cooler indoors, which may help lower heart rate, improve blood sugar control, reduce d…

This study tests whether an AI-powered chatbot can help adults aged 65 and older start and stick with a personalized exercise program. Researchers will measure changes in cognitive function, like memory and attention, over 24 weeks. Ninety participants will either get the chatbot…

This study will test whether high-intensity interval training (HIIT) on a stationary bike can improve walking, balance, and thinking in people with multiple sclerosis (MS). Forty adults with mild to moderate MS will be randomly assigned to either HIIT or moderate-intensity contin…

This study tests whether a short, telephone-delivered insomnia treatment (BBTI) can improve sleep and cognitive function in 214 older adults with HIV, compared to a mindfulness approach (BMT). Participants will complete four weekly phone sessions and attend in-person visits for s…

This study tests whether intensive music therapy can improve thinking skills like memory, attention, and decision-making in people recovering from a stroke. It will include 36 adults in Malaysia who had a stroke within the last 3 months and have mild to moderate cognitive problem…

This study will test whether doing Pilates exercises at home via video calls for 16 weeks can help people with multiple sclerosis (MS) walk farther and faster, improve balance, reduce fatigue and pain, and boost mood and thinking. About 50 adults with mild to moderate MS who can …

This study tests whether making weekly action plans for physical activity helps inactive older adults (60+) become more active and improve their memory and thinking. 148 participants will wear Fitbits for 9 months and complete brain games on their phones. Researchers compare thre…

This study tests whether two dietary supplements can help adults who are poor sleepers improve their sleep quality, thinking skills, and stress levels. Over 28 days, 68 participants will take either an active supplement or a placebo. Researchers will measure sleep efficiency, gut…

This study tests whether a non-invasive brain stimulation technique called tDCS, combined with computer-based cognitive training, can improve memory, attention, and multitasking in veterans with mild traumatic brain injury and PTSD. Forty-six veterans will receive either real or …

This study will test whether eating 1.5 cups of mango every day for 12 weeks can improve immune function and thinking skills in healthy young adults aged 18 to 30. Researchers will measure changes in immune cells, inflammation, and cognitive test scores. The goal is to see if thi…

This pilot study investigates whether exercising together or separately influences brain function, cognitive performance, mood, and parent-child connection in mother-child pairs. Mothers and their children (ages 4-12) will complete two fitness sessions—one together and one in sep…

This study looks at whether a single dose of modafinil or D-serine can improve decision-making and thinking in people who have had psychosis for less than five years. Twenty-four participants will play computer brain games and have brain scans before and after taking the drugs. T…

This study looks at how the brain works when people make decisions. Researchers will work with 30 adult epilepsy patients who already have electrodes in their brains for medical reasons. While patients play a simple decision-making game, the team will track their brain activity, …

This study reviews records from 1,000 healthy adults who completed 60 sessions of hyperbaric oxygen therapy (HBOT). Researchers will compare exercise test results and thinking skills before and after treatment to see if there are any changes. The goal is to understand how HBOT mi…

This study will create and test new ways to measure how thinking (neurocognitive load) affects arm and hand performance in athletes and healthy adults aged 18-40. Researchers will compare results from physical tests done with and without a mental challenge (reacting to lights) to…

This study looks at how doing mental tasks—like naming objects or remembering words—changes the way people with Parkinson's disease walk. Researchers will compare 30 people with Parkinson's to healthy adults of the same age and sex. The goal is to find out which type of thinking …

This observational study will use a non-invasive brain-computer interface and artificial intelligence to detect and record brain activity in terminally ill patients immediately after clinical death. Researchers aim to capture organized neurocognitive signals, such as gamma waves,…

This study will give 180 healthy adults a daily probiotic supplement (Lactobacillus plantarum) for 1 or 6 months. Researchers will collect blood and stool samples and run online cognitive tests to see if the supplement changes gut bacteria, blood markers, or thinking skills. The …

This study aims to find out how reliable the DiaMem memory test is when taken multiple times. Researchers will have 30 adults aged 60 or older take memory tests once a day for 6 days. The goal is to see if scores stay consistent, which would help doctors better assess memory prob…

This study will look at how getting only 3 hours of sleep (instead of 8) affects blood sugar, blood vessel stiffness, and thinking skills in healthy adults aged 20-45. Researchers will also test if regular exercise can help protect against these negative effects. The goal is to b…

This study will follow 2,800 adults aged 55 and older in China for many years to understand how aging affects the brain and thinking skills. Researchers will collect information on diet, lifestyle, medical history, brain scans, and gut bacteria. The goal is to learn what helps pe…

This study tests whether a mild electrical pulse to the ear (called taVNS) can temporarily improve thinking skills like attention and memory in healthy adults aged 18-30. Each of the 60 participants will receive both the real stimulation and a fake (sham) version in separate sess…

This study tests whether combining a ketosis-inducing drink with treadmill exercise can increase a brain protein called BDNF and improve thinking skills. Fifty healthy adults aged 18-35 will be given either the drink or a placebo, then exercise and take cognitive tests. The resea…

This pilot study tests whether a 6-week digital health literacy program delivered through face-to-face sessions and WhatsApp activities can help older adults in Singapore improve their digital health skills and support brain function. Researchers will compare 140 participants age…