COGNITION

This study is testing if applying a special sunlight-reflecting coating to roofs can help keep homes cooler during extreme heat in Colima, Mexico. Researchers will enroll 800 people to see if these 'cool roofs' improve physical health (like heart rate and blood sugar), mental wel…

This study aims to find the best way to help inactive older adults build lasting exercise habits and improve their memory and thinking skills. Researchers will compare three different weekly planning approaches to see which one most effectively increases physical activity and cog…

This study is testing two different phone-based programs to help older adults with HIV who have trouble sleeping. One program focuses on improving sleep habits, while the other teaches mindfulness techniques. Researchers want to see if either program can improve sleep quality and…

This study is testing whether a dietary supplement called AP-Brain can improve memory and thinking skills in healthy adults aged 40-79 who have noticed their own memory slipping. Researchers will give 120 participants either the supplement at one of three doses or a placebo (a lo…

This study is testing whether a safe, non-invasive brain stimulation technique, delivered remotely at home, can improve thinking skills like memory and attention in veterans. The treatment pairs gentle electrical stimulation with brain-training games and is designed for veterans …

This study aims to see if taking one of two nutritional supplements for 28 days can improve sleep, reduce stress, and change gut bacteria in adults who report poor sleep quality. Researchers will compare the supplements against a placebo (inactive) pill. They will measure sleep p…

This study is testing whether a dietary supplement called AP-Brain can safely improve focus, memory, and other thinking skills in healthy young adults who struggle with attention. 120 participants will take either AP-Brain at one of three doses or a placebo (a look-alike with no …

This study aims to understand how a daily probiotic supplement affects the body and mind in healthy adults. 180 participants will take the supplement for 1 or 6 months while providing blood and stool samples and completing online tasks about thinking and sleep. The goal is to see…

This study aims to find out if eating mangoes can improve immune system function and cognitive abilities like memory and focus in healthy college students. Researchers will compare two groups of young adults aged 18-30: one group will eat 1.5 servings of mango daily, while the ot…

This study is testing a new 6-week program called WISDOM that uses WhatsApp and in-person sessions to teach older adults how to find and use reliable health information online. Researchers want to see if this program is practical to run and if it helps improve participants' digit…

This study aims to understand if taking a supplement to induce ketosis (a metabolic state) combined with exercise can increase a key brain chemical (BDNF) and improve thinking skills. It will specifically check if people with a certain genetic trait (the Met allele) benefit more.…

This study aims to understand if a gentle, non-invasive stimulation of the ear (called taVNS) can temporarily improve thinking skills like memory and focus in healthy adults. It will compare the effects of real stimulation to a fake (sham) version in 60 participants, and also che…

This study aims to see if it's possible to detect and record organized brain activity in people immediately after their heart stops, but before brain death is declared. Researchers will use a special, non-invasive EEG headset and artificial intelligence to monitor about 20 adults…

This study aims to understand how decision-making works in people with recent psychosis. Researchers will give 24 participants single doses of two different drugs (modafinil and d-serine) and a placebo during separate visits. They will use brain scans and computer games to see if…

This study aims to see how reliable a new digital memory test called DiaMem is when the same person takes it multiple times. Researchers will enroll 30 adults aged 60 or older to take memory tests daily for six days. The goal is to understand if the test gives consistent results …

This study aims to understand if people who exercise regularly are better protected from the negative health effects of a short night's sleep. Researchers will compare how sleep deprivation affects blood sugar control, blood vessel health, and thinking skills in 48 healthy adults…

This long-term study aims to understand why some people develop memory and thinking problems as they age while others do not. Researchers will follow 2,800 adults aged 55 and older, including those with healthy brains and those with early signs of cognitive decline. They will col…