COGNITION
Clinical trials for COGNITION explained in plain language.
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Pistachio power: daily nut snack may boost brain and heart in seniors
Disease control OngoingThis study looks at whether adding pistachios to the daily diet for 6 months can improve memory, thinking speed, and other brain functions in adults aged 65 to 80. It also checks for changes in blood pressure and overall life satisfaction. About 97 participants who are already in…
Matched conditions: COGNITION
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Simple drug may stop Post-Surgery brain fog in High-Risk patients
Disease control OngoingThis study tests whether giving tranexamic acid before major gastrointestinal surgery can lower the chance of delirium (sudden confusion) after the operation. Delirium is common in older or sicker patients and may be caused by inflammation harming the brain. The trial includes 82…
Matched conditions: COGNITION
Phase: PHASE3 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Brain games may shield seniors with diabetes from memory loss
Disease control ENROLLING_BY_INVITATIONThis study tests whether a computerized brain-training program can improve thinking skills in older adults (60+) who have type 2 diabetes and are at high risk for dementia. 120 participants will be randomly assigned to either adaptive cognitive training or a placebo version, both…
Matched conditions: COGNITION
Phase: NA • Sponsor: Fanfan Zheng • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Brain and body boost: Dual-Task training may ease Parkinson's symptoms
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding cognitive training to balance and gait exercises helps people with Parkinson's disease improve their balance, walking, and thinking. Fourteen participants will undergo 12 sessions of combined training. The goal is to see if this approach eases move…
Matched conditions: COGNITION
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Whey to go? protein drink tested to fight frailty in seniors
Symptom relief OngoingThis pilot study is testing whether taking 24 grams of whey protein daily for three months can improve brain antioxidant levels, physical function, and thinking skills in pre-frail adults aged 65 to 85. Twenty participants will be randomly assigned to receive either whey protein …
Matched conditions: COGNITION
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Rosemary oil may sharpen memory, small trial hints
Symptom relief OngoingThis study tests whether inhaling rosemary essential oil can improve memory, attention, and other thinking skills in healthy adults. 63 participants will either sniff rosemary oil or a placebo for 14 days and take brain tests before and after. The goal is to see if this natural r…
Matched conditions: COGNITION
Phase: NA • Sponsor: Federal University of Paraíba • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Virtual reality could ease fear of shock therapy
Symptom relief OngoingThis study tests whether watching a virtual reality (VR) video of an electroconvulsive therapy (ECT) session can reduce anxiety and improve knowledge about the procedure. About 64 adults about to have ECT for the first time will be randomly assigned to either a VR education sessi…
Matched conditions: COGNITION
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Dance class may ease Parkinson's 'OFF-Time' and boost brain power
Symptom relief OngoingThis study tests whether partnered dance aerobic exercise can reduce 'OFF-time' (when Parkinson's medication stops working well) and improve thinking skills. Researchers will enroll 82 people with Parkinson's who experience OFF-time. Participants will take dance classes twice a w…
Matched conditions: COGNITION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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New therapy aims to keep seniors on their feet
Symptom relief ENROLLING_BY_INVITATIONThis study tests a 12-session personalized program for adults 65 and older who have fallen at least once in the past year. The program focuses on balance, safe walking, home adjustments, and activities that matter to each person. Researchers will measure improvements in balance, …
Matched conditions: COGNITION
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Brain fog in fibromyalgia: study probes hidden links to thinking skills
Knowledge-focused ENROLLING_BY_INVITATIONThis study investigates factors that may influence cognitive skills—like memory, attention, and problem-solving—in women diagnosed with fibromyalgia. Researchers will assess thinking abilities using a detailed cognitive test and measure how fibromyalgia affects daily life. The go…
Matched conditions: COGNITION
Sponsor: Zülal TATAR • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Personalized digital coaching may boost adherence to brain-healthy lifestyle changes
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether personalized digital coaching helps people stick to brain-healthy habits like exercise, diet, and sleep. 120 adults at risk for cognitive decline will be assigned to generic education, a digital platform, or the platform plus health coaching. The goal is …
Matched conditions: COGNITION
Phase: NA • Sponsor: Institut Guttmann • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New turkish scale aims to measure thinking problems in Parkinson's
Knowledge-focused ENROLLING_BY_INVITATIONThis study translates a scale that measures how thinking difficulties affect daily life in people with Parkinson's disease into Turkish. Researchers will test the translated version in 60 Turkish-speaking Parkinson's patients to see if it is valid and reliable. The goal is to giv…
Matched conditions: COGNITION
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Can we track brain health in older cancer patients?
Knowledge-focused OngoingThis study looks at whether it's possible to track memory and thinking changes in adults aged 65 and older who are starting a new type of cancer treatment called immune checkpoint inhibitors. Thirty participants will take simple memory and concentration tests every six weeks for …
Matched conditions: COGNITION
Sponsor: Our Lady's Hospice and Care Services • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Brain zaps: can sound waves tweak your thinking?
Knowledge-focused OngoingThis study looks at how focused ultrasound (sound waves) aimed at the cerebellum changes brain activity and thinking in 20 healthy adults aged 18 to 40. Participants do thinking tasks after real or fake ultrasound. The goal is to learn how the cerebellum affects brain function, n…
Matched conditions: COGNITION
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Scientists probe brain waves to decode human thought
Knowledge-focused ENROLLING_BY_INVITATIONThis study measures brain activity and chemical levels in people with epilepsy who already have electrodes implanted for medical reasons. Participants play simple computer games while their brain signals are recorded. The goal is to learn how the brain works during thinking and e…
Matched conditions: COGNITION
Phase: NA • Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC