COGNITION

This study tests whether giving tranexamic acid before major gastrointestinal surgery can lower the chance of delirium (sudden confusion) after the operation. Delirium is common in older or frail patients and may be caused by inflammation harming the brain. The trial involves 826…

This study tests whether a digital platform called ToBrainHealth can help people aged 40-75 adopt and stick to brain-healthy habits like exercise, better sleep, and social activities. 120 volunteers will be split into three groups: one gets general advice, another gets personaliz…

This study tests whether a special computer-based brain training program can improve memory and thinking in older adults (60+) who have type 2 diabetes and are at high risk for dementia. 120 participants will be randomly assigned to either the adaptive training or a placebo versi…

This study tests whether watching a virtual reality (VR) video of an ECT session can reduce anxiety and improve understanding in people about to receive ECT for the first time. About 64 participants will be randomly assigned to either the VR experience or a standard talk with a p…

This study looks at whether smelling rosemary essential oil can help healthy adults think better. Researchers will test memory and attention after a single use and after two weeks of daily use. The goal is to see if rosemary oil is a simple, natural way to support brain function.

This study tests a 12-session personalized program for adults 65 and older who have fallen at least once in the past year. The program focuses on balance, gait, home safety, and daily activities that matter to each person. Researchers will measure changes in balance, mobility, an…

This study looks at whether partnered dance aerobic exercise can improve movement and thinking in people with Parkinson's disease. About 82 participants will take part in dance sessions or other activities. The goal is to see if dancing can reduce "OFF-time" when medications don'…

This study looks at whether adding specific cognitive (thinking) exercises to balance and walking training can improve balance, walking, and mental function in people with Parkinson's disease. Fourteen participants with mild to moderate Parkinson's will undergo 12 training sessio…

This study translates a scale that measures how thinking problems affect daily life in people with Parkinson's disease into Turkish and checks if it is accurate and reliable. About 60 people with mild to moderate Parkinson's will take part. The goal is to give doctors a better to…

This study looks at whether it is possible to track memory and concentration changes in adults aged 65 and older who are starting a type of cancer treatment called immune checkpoint inhibitors. Over six months, 30 participants will take simple memory and thinking tests every six …

This study measures brain activity and chemical levels in people with epilepsy who already have electrodes implanted for medical reasons. Participants play simple computer games while their brain signals are recorded. The goal is to better understand how the brain works during th…

This study looks at whether adding pistachios to the daily diet for 6 months can improve memory, thinking speed, and heart health in adults aged 65 to 80. About 97 participants will eat pistachios and take tests on thinking, blood pressure, and life satisfaction. The goal is to s…

This study looks at how a gentle ultrasound pulse to the cerebellum (the part of the brain that controls coordination and some thinking) changes brain waves and mental tasks. Twenty healthy adults aged 18 to 40 will receive both real and fake (sham) ultrasound while their brain a…