Simple drug may stop Post-Surgery brain fog in High-Risk patients
NCT ID NCT05470816
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving tranexamic acid before major gastrointestinal surgery can lower the chance of delirium (sudden confusion) after the operation. Delirium is common in older or sicker patients and may be caused by inflammation harming the brain. The trial includes 826 adults with two or more risk factors, such as age 70+ or diabetes, and compares the drug to a placebo. The goal is to see if this simple, safe medication can protect brain function and improve recovery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alfred Health
Melbourne, Victoria, 3181, Australia
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