Simple drug may stop Post-Surgery brain fog in High-Risk patients
NCT ID NCT05470816
First seen Jan 05, 2026 · Last updated Jun 17, 2026 · Updated 23 times
Summary
This study tests whether giving tranexamic acid before major gastrointestinal surgery can lower the chance of delirium (sudden confusion) after the operation. Delirium is common in older or sicker patients and may be caused by inflammation harming the brain. The trial includes 826 adults with two or more risk factors, such as age 70+ or diabetes, and compares the drug to a placebo. The goal is to see if this simple, safe medication can protect brain function and improve recovery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Alfred Health
Melbourne, Victoria, 3181, Australia
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.