Can a daily probiotic change your gut and brain? new study investigates

NCT ID NCT07457242

Not yet recruiting Knowledge-focused Sponsor: OneCarbon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will give 180 healthy adults a daily probiotic supplement (Lactobacillus plantarum) for 1 or 6 months. Researchers will collect blood and stool samples and run online cognitive tests to see if the supplement changes gut bacteria, blood markers, or thinking skills. The goal is to learn more about how probiotics affect the body and mind, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Lactobacillus plantarum probiotic supplement
What this could lead to
If successful, this could help researchers understand how probiotics influence gut bacteria, blood markers, and brain function in healthy people.
What could go wrong
This is a small, early pilot study with no control group, so results may not be conclusive. The supplement is not intended to treat any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Psychological Well-Being sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.