Brain games and drugs: a new hope for psychosis?

NCT ID NCT07263022

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a single dose of modafinil or D-serine can improve decision-making and thinking in people who have had psychosis for less than five years. Twenty-four participants will play computer brain games and have brain scans before and after taking the drugs. The goal is to understand how these agents affect the brain, not to treat the condition directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Modafinil and D-serine

What this could lead to

If it works, this could point toward treatments that improve thinking and decision-making in people with early psychosis.

What could go wrong

This is a small, early-stage study with only 24 participants. It tests single doses, not long-term effects, so results may not lead to new treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bipolar disorder cognitive disorder major depressive disorder psychiatric disorder psychotic disorder Psychotic Disorders schizoaffective disorder schizophrenia schizophreniform disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••