Zap your brain at home to fight dementia?

NCT ID NCT06821568

Recruiting now Symptom relief Sponsor: Hebrew SeniorLife Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study tests whether 6 months of daily, home-based transcranial direct current stimulation (tDCS) can improve cognitive and motor function in 128 older adults (ages 65-90) with motoric cognitive risk syndrome, a condition that raises dementia risk. Participants use a headset that delivers either real or sham stimulation to the left prefrontal cortex. The main goal is to see if it helps with walking while doing a mental task, with secondary measures of executive function and gait speed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial direct current stimulation (tDCS)
What this could lead to: If it works, this could offer a safe, at-home way to slow cognitive decline and improve mobility in older adults at risk for dementia.
What could go wrong: This is an early-stage study with only 128 participants, so results may not apply to everyone. The stimulation may not produce meaningful benefits, and the sham group helps control for placebo effects.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease anxiety disorder Atrophy Behavior Cognition Disorders cognitive disorder dementia syndromic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE AND RELATED DEMENTIAS COGNITION MOBILITY DISABILITY

Contacts and locations

Locations

Hebrew Rehabilitation Center
RECRUITING

Roslindale, Massachusetts, 02131, United States
Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, Israel

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