Brain insulin study aims to unlock antipsychotic side effects

NCT ID NCT07109245

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the antipsychotic medication haloperidol may block insulin action in the brain, which could explain why these drugs often cause weight gain and diabetes. Researchers will give healthy volunteers either haloperidol or a placebo and use brain scans to measure changes. The goal is to understand the mechanism so future treatments can be safer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, M6J 1H3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••